Words similar to mhc

Example sentences for: mhc

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Early during T-cell development in the thymic cortex, thymocytes bear both of the T cell surface glycoproteins CD4 and CD8 and express the α and β heterodimer of the TCR [ 4 ] . Compelling data have demonstrated that CD4 and CD8 molecules participate in the selection of MHC class I or class II restricted T cells in the thymus.
Changing the interaction of peptide, MHC class II molecules, T cell receptors and other antigen-presenting cell specific ligand interactions to foster stronger, higher affinity T cell signalling has been shown in mice to skew T cell differentiation from Th2 to Th1-like patterns [ 40 41 42 43 44 45 46 47 48 49 50 ] . Differences in Th-differentiation patterns have downstream effects on the type of immune response mounted, and in particular on the isotypes of antibody expressed.
7 with a construct in which IDO was expressed under the control of the murine MHC Class II promoter (Fig 1A).
The mean percentage compositions of mRNA representing each MHC isoform in the diaphragms of emphysematous and control animals are listed in Table 1. Note that there was a significant decrease in the expression of MHC IIb in emphysematous versus control.
2002), or genes encoding reconnaissance molecules known as the major histocompatibility complex (MHC), which control the action of T-cells (Hughes and Nei 1988; Yeager and Hughes 1999) (Box 1).