Words similar to mirna

Example sentences for: mirna

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As a complementary approach to miRNA identification, we developed an informatic strategy ('miRseeker') and applied it to the completed genomes of Drosophila melanogaster and D. pseudoobscura , which are some 30 million years diverged.
In these heady times of miRNA gene discovery, it is prudent to exercise caution in designating predicted genes as bona fide , just because they resemble known miRNA genes [ 46 ] . At the same time, while many thousands of annotated protein-coding genes are not associated with cDNA clones or other evidence of expression, computational methods of their identification are robust enough for them to be considered 'real' genes until proven otherwise.
We stress that the conservation consideration described above applies only to appropriately related species (such as Dm/Dp ) and should not be indiscriminately used to filter miRNA candidates derived from comparative analysis of other species.
Of the reference set miRNAs, only mir-2b-1 failed these filters (as a class 6 miRNA), even though it received the eighth highest score of all super-regions in the entire euchromatic sequence of the drosophilid genomes.
The largest cluster of miRNA genes in Drosophila includes six that were previously identified as the mir-3 → mir-6-3 cluster [ 10 ] . We identified two additional conserved stem-loop structures that flank mir-3 (Figure 7a), one of which ( mir-286 ) was confirmed by northern blot (Figure 5a).