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Example sentences for: mirna

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The volatility of miRNA genes is further indicated by members of the miR-2/miR-13 K box subfamily [ 47 ] . Seven members were previously reported that are scattered in four genomic locations on three different chromosome arms, including a cluster of three mir-2 genes on 2L and a cluster of two mir-13 genes on 3R; we also identified an additional paralog of mir-2 ( mir-2c ) that is located in the mir-13 cluster.
Of the reference set miRNAs, only mir-2b-1 failed these filters (as a class 6 miRNA), even though it received the eighth highest score of all super-regions in the entire euchromatic sequence of the drosophilid genomes.
First, the mature miRNA can be derived from either arm of a given stem-loop, and many predicted pre-miRNAs fold well on either strand.
In theory, a computational approach based on the structural features of known miRNA genes might permit the unbiased discovery of the remaining complement of miRNA genes in a given sequenced genome.
We found that a 100-unit segment of the alignment (where a unit is either a single paired or gapped nucleotide) containing no more than 13% gaps or 15% mismatches, was sufficient to identify all known miRNA genes within their respective genomic neighborhoods, with a minimum of additionally selected sequences.