Words similar to mirna

Example sentences for: mirna

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The largest cluster of miRNA genes in Drosophila includes six that were previously identified as the mir-3 → mir-6-3 cluster [ 10 ] . We identified two additional conserved stem-loop structures that flank mir-3 (Figure 7a), one of which ( mir-286 ) was confirmed by northern blot (Figure 5a).
We took care to verify that our windowing parameters segregated individual miRNAs within known miRNA clusters (the mir-2 , mir-13 and mir-3 → mir-6 clusters [ 10 ] ) into distinct super-regions.
Unexpectedly, we did not find that clusters of paralogous miRNA genes were more prevalent, as might have been predicted a priori if gene clusters generally result from local gene duplications.
Surprisingly, mir-286 is the only member of this seven-miRNA cluster that is conserved in Anopheles , indicating tremendous flux in the miRNA content of this region even within the Diptera.
In this study, we describe miRseeker, a computational approach for the identification of Drosophila miRNA genes that ranks conserved stem-loop structures and assesses their pattern of nucleotide divergence.