Words similar to mirna
Example sentences for: mirna
How can you use “mirna” in a sentence? Here are some example sentences to help you improve your vocabulary:
Incorporation of promoter evidence in gene models may also help, given recent speculation that miRNA genes may be transcribed by RNA polymerase II.
In general, it is thought that miRNA biogenesis proceeds via intermediate precursor transcripts of more than 70 nucleotides that have the capacity to form an extended stem-loop structure (pre-miRNA), although at least some pre-miRNAs are further derived from even longer transcripts (primary miRNA transcripts, or pri-miRNAs).
As we tested one or two probes for each candidate, a false-negative result will have been obtained if we tested either the incorrect arm or strand of a putative miRNA.
First, the mature miRNA can be derived from either arm of a given stem-loop, and many predicted pre-miRNAs fold well on either strand.
We found that a 100-unit segment of the alignment (where a unit is either a single paired or gapped nucleotide) containing no more than 13% gaps or 15% mismatches, was sufficient to identify all known miRNA genes within their respective genomic neighborhoods, with a minimum of additionally selected sequences.