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Example sentences for: mir-

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The volatility of miRNA genes is further indicated by members of the miR-2/miR-13 K box subfamily [ 47 ] . Seven members were previously reported that are scattered in four genomic locations on three different chromosome arms, including a cluster of three mir-2 genes on 2L and a cluster of two mir-13 genes on 3R; we also identified an additional paralog of mir-2 ( mir-2c ) that is located in the mir-13 cluster.
As mentioned earlier, one of the 24 reference miRNAs (miR-10) did not reside in an aligned region, even though it was readily identified in available D. pseudoobscura sequence by BLAST query.
The characteristics of miR-100 are highly unusual and thus serve as a useful caution.
While this work was under review, the clustering of miR-100, let-7 and miR-125 was independently reported; these researchers also provide evidence for coordinate expression of these miRNAs as a single pri-miRNA [ 45 50 ] .
This contrasts with observations of miRNAs in vertebrates, where the majority of known miRNAs are members of paralogous gene sets [ 31 ] . The most extreme examples of this disparity are let-7 and mir-29 , which are present in single copies in Drosophila , but are represented by thirteen and six distinct human homologs, respectively.