Words similar to mhc-restricted
Example sentences for: mhc-restricted
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Some researchers have reported the ability of CD56 positive T cells to exhibit spontaneous killing against some of the targets such as K562 or P815, upon stimulation with IL-2 [ 22 23 24 25 ] . However Lanier and Philips who carried out extensive studies on the LAK phenomenon have emphasised that although CD16+ T cells exhibit non-MHC-restricted cytotoxicity to some targets upon IL-2 stimulation, their contribution was quantitatively and qualitatively very minimal as compared to the NK subset [ 7 11 ] . The differences in the ability of lymphocytes of different phenotypes to respond to IL-2 stimulation and carry out spontaneous lysis of different targets could probably be attributed to the differential expression of inhibitory receptors present on the targets such as KIR and CD94:NKG2 [ 26 ] .