Example sentences for: mediators

How can you use “mediators” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Several factors may account for this variability: at the time of investigation, endogenous vasoconstricting mediators involved in pulmonary artery hypertension were probably different between patients.

  • The neurotransmitters dopamine, histamine, acetylcholine, and serotonin are important mediators of this symptom complex.

  • In pulmonary emphysema, various inflammatory mediators have been suggested to cause tissue destruction and loss of structure [ 12, 13, 14, 15].

  • A notable finding from our study is that exposure of NHBEs to CSC elicits the synthesis and release of a pattern of mediators similar to that seen in A549 cells in response to CSC.

  • In this regard, recent studies have shown that inflammatory mediators such as lipopolysaccharide (LPS), granulocyte macrophage-colony stimulating factor and leukotriene B 4 delay apoptosis and prolong neutrophil survival in culture [ 3 4 ] . Neutrophils migrating into rodent lungs in response to LPS challenge have also been reported to exhibit delayed rates of apoptosis [ 5 6 ] . Similarly, increases in cytokine and growth factor activity, and reduced neutrophil apoptosis, have been described in various inflammatory lung diseases in humans including chronic obstructive pulmonary disease, acute respiratory distress syndrome and pneumonia [ 3 7 8 ] .


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