Example sentences for: mediators

How can you use “mediators” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Tumour necrosis factor-α blockade reduces synovial expression of CCL2 and CXCL8 and reduces inflammatory cell migration into RA joints [ 9 ] . In addition, these chemokines, produced by RA synovial stromal cells, have been shown to stimulate monocyte migration [ 10 ] . The functional importance of chemokines in joint inflammation has also been established in animal models of RA where antibodies to these mediators significantly reduce both the number of leukocytes recruited and the severity of disease.

  • The neurotransmitters dopamine, histamine, acetylcholine, and serotonin are important mediators of this symptom complex.

  • We have recently reported on the kinetics of LPS activation of rat neonatal microglia and the concomitant release of TNF-α protein, MMP-9 and O 2 - [ 7 ] . These three microglia mediators are currently thought to participate in neuronal and glial injury in vivo [ 10 45 ] .

  • And since perhaps the most disliked mediators out there are car dealers, they would seem to be natural and inevitable casualties of consumers' migration to the Internet.

  • However, what this meant for relative transport of RU486 or maternal mediators of fetal hormone balance upon adrenalectomy is unknown.


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