Example sentences for: mediators

How can you use “mediators” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • In the present work, the focus will be on transcription factors previously identified as mediators of LC-PUFA actions, such as PPARs, SREBP, and HNFs.

  • The cysteinyl leukotrienes (CysLT), LTC, LTD, and LTE, were first shown to be essential mediators in asthma [ 29 ] . However, when the mouse leukotriene B4 receptor (m-BLTR) gene, was cloned it was shown to have significant sequence homology with chemokine receptors (CCR5 and CXCR4), co-receptors for many different HIV-1 clades [ 30 ] . Along the same lines, when cells were infected with 10 primary clinical isolates of HIV-1, leukotriene B4 receptor was primarily utilized for efficient entry into cells which were mainly of the syncytium-inducing phenotype [ 31 ] . Therefore, up-regulation of neuropeptide Y-like receptor and down-regulation of leukotriene B4 receptor in Tat expressing cells indicates a selective advantage of one class of virus (CCR5) over another (CXCR4).

  • However, since initial MAP levels were not established in the study groups, it is possible that some other mediators were affecting blood pressure at the start of the experiment.

  • 9), other viral proteins and many cellular entities may act as important mediators at various steps.

  • 1) A tool whose design, content, and clinical saliency address the behavioral capability, expectation, and self-efficacy deficits of physicians, as these constructs are significant mediators of physician behavior;


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