Example sentences for: mediates

How can you use “mediates” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The phosphorylated beta-2 receptor enhances the binding of beta-arrestin, which not only uncouples the receptor from the signal transduction process but also serves as an adapter protein that mediates entry into the internalization pathway [ 5 ] , as well as serving as a platform for additional signaling pathways [ 6 ] . The mechanisms of beta-2 adrenergic receptor down-regulation appear to involve both an increase in the rate of degradation of the receptor as well as a decrease in the levels of beta receptor mRNA [ 7 ] . Down-regulation of the beta-2 receptor is, in part, due to trafficking of the beta-2 receptor to lysosomes via the clathrin-coated pit endosomal pathway [ 8 9 ] .

  • RSS variability has important functional consequences: the efficiency with which each RSS mediates recombination depends on its sequence [ 46].

  • [ 30] indicate that TPC1 is a two-pore channel that mediates Ca 2+influx.

  • CD36 protein mediates long chain free FA uptake in adipocytes and other tissues, including liver.

  • TNF overproduction mediates both sepsis and chronic inflammatory disorders such as RA.


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