Example sentences for: mediates

How can you use “mediates” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • In the present study, we show for the first time, to our knowledge, that CD36 mediates apoptosis in differentiated epithelial cells that are exposed to AGE-BSA-, CMLmin-BSA-, and FFA-induced metabolic injury characteristic of the diabetic milieu.

  • Each contains an SH3 domain; a SAM (sterile alpha motif) domain; a proline-rich region, which mediates binding to the second SH3 domain of Bem1; and a PH domain [ 1 2 3 ] . Figure 1shows the relative positions of these sequence features in Boi1.

  • SLC/CCL21 is documented to have direct anti-angiogenic effects [ 28 29 ] ; the tumor reductions observed in this model could have been due to participation by T cells secreting IFNγ leading to inhibition of angiogenesis via MIG/CXCL9 and IP-10/CXCL10, as well as T cell-dependent immunity [ 16 ] . IFNγ mediates a range of biological effects that facilitate anticancer immunity.

  • CD36 protein mediates long chain free FA uptake in adipocytes and other tissues, including liver.

  • As this region of the protein is likely to contain a conserved globular domain that mediates other functional interactions of these proteins, we sought to investigate its complete diversity and potential evolutionary connections.


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