Words similar to mediator
Example sentences for: mediator
How can you use “mediator” in a sentence? Here are some example sentences to help you improve your vocabulary:
An accumulation of 4-HNE-conjugated protein has been detected in lesions of aging-related diseases, including Parkinson's disease [ 53 ] and Alzheimer's disease [ 54 ] . It also accumulates in the affected neuronal tissues of experimental animals experiencing brain ischemia [ 55 56 ] and traumatic spinal cord injury [ 57 ] . 4-HNE can impair synaptosomal membrane proteins, glutamate transport and importantly, mitochondrial functions [ 58 59 ] . Evidence indicates that 4-HNE increases neuronal susceptibility to oxidative stress [ 60 ] and serves as a mediator of oxidative stress that leads to neuronal apoptosis [ 61 ] . As indicated in the Introduction, 4-HNE has been implicated in some ocular pathological conditions [ 19 20 ] .
According to the Times of London, the mediator is widely thought to be Padraig Wilson, a former head of IRA inmates in the Maze prison in Belfast.
Nevertheless, the results seen in opposite directions in uterus and colorectum suggest that estrogen exposure at least up to the point at which BMD was measured was a significant mediator of risk for cancer in NHANES I. The weakly positive results for breast cancer in combination with previously published reports suggest that, unlike the other endpoints reported herein, BMD as a predictor of breast cancer risk is only of use when measured after menopause.
Furthermore, CDDO decreased the expression of the pro-inflammatory mediator Bcl-3, suggesting one possible mechanism of action.
We speculate that NF-κB and CREB regulate the activity of biochemical signals leading to prolonged survival and inflammatory mediator production in the lung.
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