Example sentences for: mediated

How can you use “mediated” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • In mammals, the positive elements are two basic helix-loop-helix (bHLH) PAS-domain-containing transcription factors, CLOCK and BMAL1, that form heterodimers that can drive the transcription of three period ( per ) genes per1-3 and two cryptochromes ( cry1,2 ). PER1,2 and CRY1,2 proteins suppress CLOCK:BMAL1-mediated transcription thereby forming the negative elements in the feedback loop.

  • Abscisic acid response elements (ABREs) are important during the plant's response to abiotic stresses such as dehydration, salinity and cold, all of which are ABA-mediated [ 82 83 ] . There is evidence that ROS are involved in ABA signaling [ 84 ] . The enrichment of the ABRE motif in the promoter sequences of the genes in the stress cDNA collection may reflect crosstalk among stress signaling pathways mediated by common second messengers, such as H 2 O 2 . The over-representation of the SA-inducible element in the promoter sequences of the genes in the stress cDNA collection, especially those in the SA library, further validates the enrichment of the stressor-specific genes using the SSH technique and suggests that these genes may be regulated by the changes in the levels of SA that occurs in stress responses [ 85 ] .

  • This level of regulation could be mediated via second messenger control of autophosphorylation, or via direct MHCK-C phosphorylation by other kinases.

  • These genes encode Ca 2+-activated K +channels of large conductance, intermediate conductance and small conductance: these are thought to be mediated by Slo, slack and SK channels, respectively.

  • Thus, the second step in the computation of direction selectivity, i.e. the subtraction, is mediated by the opponent interaction between T4- and T5 cell input on the dendrites of each LPTC.


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