Words similar to mediating
Example sentences for: mediating
How can you use “mediating” in a sentence? Here are some example sentences to help you improve your vocabulary:
Expression of this G S -coupled cAMP-stimulating PGE 2 receptor in cultured vascular smooth muscle cells isolated from the aorta supports a direct role of the EP 2 receptor in mediating vascular relaxation.
DEK is a nuclear protein that is not structurally related to any known family of proteins [ 12 13 ] . Although it may also participate in DNA replication and RNA processing [ 14 15 ] , we have identified DEK as a DNA-binding protein that recognizes the TG-rich peri- ets (pets) regulatory element in the human immunodeficiency virus type 2 (HIV-2) enhancer [ 16 ] . The pets site is important in mediating HIV-2 enhancer stimulation in activated T cells and monocytes [ 17 18 19 ] , suggesting that DEK may play an immunomodulatory role as it participates in transcriptional activation through this and related sites.
Specifically, we show that glucose stimulates CD36 cell surface expression in proximal tubular epithelial cells (PTECs), and increased CD36 renders PTECs susceptible to both AGE- and PA-induced PTEC apoptosis by mediating sequential activation of src kinase, proapoptotic p38 MAPK, and caspase 3. Based on these findings, we propose a new two-step metabolic hit model for TED in the progression of DNP.
In concert, TNF-α and TRANCE expressed by this subset of CD4 +memory T cells might make them particularly important in mediating the bony erosions that are characteristic of RA.
The presence of a divergent SWIRM domain, linked to a HORMA domain, in Asy1, the plant ortholog of the yeast Hop1p [ 36], is consistent with the role of these proteins in mediating protein-protein interactions in the process of chromosome synapsis [ 42].
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