Example sentences for: mediate

How can you use “mediate” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Instead, CIP8, an AtCOP1 interacting RING-H2 finger protein, is found to ubiquitinate HY5 in vitro [ 50 51 ] . Therefore, it is possible that COP1 may recruit other RING finger proteins, such as CIP8, to mediate the ubiquitination of specific substrates.

  • Well studied examples of these are the bromodomain that interacts with acetylated peptides [ 14, 15, 16], chromodomains that mediate specific interactions with proteins [ 17, 18] and RNA [ 19, 20], the PHD finger mediating protein-protein interactions [ 21], the Myb and SANT domains [ 22] that interact with both DNA and proteins [ 23], and the SAP and AT-hook domains that interact with DNA [ 24, 25].

  • Such deletions are apparently irreversible in obligate mutualists, which lack recombination functions and genetic elements, such as prophages, transposons, and repetitive DNA that typically mediate gene acquisition.

  • In addition, this domain also appears to mediate specific protein-protein interactions.

  • Smads have been shown to mediate transcription via modulating the transcriptional activity of many other DNA-binding proteins.


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