Words similar to lysosomal
Example sentences for: lysosomal
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Although direct measurements of lysosomal oxidative activity in live cells were not available before the present study, several lines of evidence did point to a regulatory mechanism in phagolysosomes or lysosomes in phagocytes during phagocytosis and oxidative burst.
As shown in Table 1, the average pH in total lysosomal population significantly increased (0.
For example, deficiencies of various enzymes responsible for lipid metabolism result in lipid accumulation in lysosomal storage diseases such as Niemann-Pick and Gaucher diseases [ 2 ] . Alternatively, modulation of lysosomal lumen pH may alter membrane trafficking and associated metabolic processes.
It has been reported that elevated lysosomal pH is associated with the genetic lysosomal disorder, Mucolipidosis type IV disease where various sphingolipids and mucolipids accumulate in the lysosome [ 3 ] . Finally, lysosomes may play multiple roles in cellular oxidative metabolism [ 4 ] . The oxidative activity in lysosomes may regulate the modification of proteins and lipids, resulting in disruption of lysosomal membrane integrity [ 5 ] .
Like testicular PH-20, lysosomal Hyal-1 and Hyal-2 enhanced TNF susceptibility in L929 cells.