Words similar to lysosomes
Example sentences for: lysosomes
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Fluorescence of fluorescein and its analogs such as carboxyfluorescein has been shown to be pH-dependent [ 10 11 ] . Elevation of pH increases the ratio of fluorescent emission at λ 535 as excited by λ 485 over λ 440 . The heterogeneous fluorescence of the oxidized dye in subsets of lysosomes where it exhibits a significant difference in pH (4.
The LysoTracker Red DND-99 is a fluorescent analog of chloroquine, which selectively accumulates in lysosomes [ 9 ] . Cells were incubated with a 25 nM concentration of the dye at 37°C for 5 min.
This decrease in fluorescence is due to a decrease in accumulation of the dye in lysosomes since the change in pH itself has no effect on the fluorescence of the dye (data not shown).
It is composed of a cytoplasmic ATPase domain called V 1 that contains VhaSFD and other subunits, and a multisubunit membrane-channel component called V 0 . The vacuolar ATPase is involved in the acidification and energization of organelles such as Golgi-derived vesicles, clathrin-coated vesicles, synaptic vesicles and lysosomes.
It is also possible that the heterogeneous distribution of fluorescence intensity of oxidized OxyBURST Green H 2 HFF BSA is due to preferential accumulation of the reduced dye in a subset of lysosomes rather than being determined by a variation of oxidative activity in these lysosomes.