Example sentences for: lysosome

How can you use “lysosome” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Transient expression of GFP-Hyal-2 in COS7 fibroblasts showed the localization of the expressed protein in the lysosome but not in the mitochondria, as determined by staining the cells using LysoTracker and Mitotracker Red (data not shown).

  • Also, the cells were counterstained with LysoTracker or Mitotracker Red (Molecular Probes, Eugene, OR) to determine whether the expressed protein was located in the lysosome or mitochondria.

  • Recent evidence points, instead, to an important role of the lysosome, the other major pathway within cells for degrading unwanted proteins, in clearing α-synuclein (Cuervo et al.

  • Hyal-2 is found in the lysosome and is active under conditions of low pH [ 20 ] . Hyal-2 is also found on the cell surface as a glycosylphosphatidylinositol (GPI)-anchored receptor for jaagsiekte sheep retrovirus [ 21 ] . Nonetheless, the enzymatic activity of Hyal-2 has not been detected [ 21 ] . Whether the increased TNF cytotoxicity in L929 cells caused by Hyal-1 and Hyal-2 is associated with their enzymatic activities is being studied in this laboratory.

  • Furthermore, since the charged free radical O 2 •-should have difficulty leaking across hydrophobic membranes, formation of this anion radical inside the lysosome may have an immediate impact on pH in this organelle.


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