Example sentences for: interaction

How can you use “interaction” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Specific CD98-integrin interaction occurs in the context of low density protein-lipid microdomains, possibly resembling lipid rafts [ 34 35 ] . Several important signaling molecules, including activated TCR, LAT and LCK are present in organized raft-type microdomains, and integrity of these microdomains is necessary for T cell receptor signal transduction [ 36 37 ] . Our present discovery that β1 integrins specifically associate with CD98 in lipid microdomains helps to explain the functional connections between β1 integrins and CD98 during T cell costimulation, monocyte fusion, and elsewhere.

  • The 1.0 MDa complex contains yCCR4, yPOP2 (also referred to as yCAF1) and at least five yNOT1-5 proteins [ 5 6 7 ] . In this complex, yPOP2 independently binds to yCCR4 and yNOT1, and is absolutely required for yCCR4 to associate with the 1.0 MDa complex [ 6 7 ] . In the 1.9 MDa complex, yCCR4 binds to proteins such as yDBF2, a cell-cycle regulated protein kinase [ 2 ] , yCAF4 and yCAF16, and is essential for the interaction of both yCAF4 and yCAF16 with ySRB9, a component of the RNA polII holoenzyme [ 8 ] . yCCR4 was also reported to be associated with Paf1, Cdc73, and Hpr1 in a RNA polII complex distinct from the SRBP-containing holoenzyme [ 9 ] . Accordingly, yCCR4 contains, in its central region, a leucine-rich repeat (LRR) domain [ 10 ] which was demonstrated to be necessary for yCCR4 binding to the yPOP2 [ 5 11 ] , yDBF2 [ 2 ] , yCAF4 and yCAF16 [ 8 ] components of the CCR4-NOT complex.

  • The number of potential Zn(II) binding cysteine motifs range from none in S. cerevisiae DNA topoisomerase III to four highly conserved tetracysteine motifs in the beta family of the topoisomerase III enzymes [ 38 ] . The Zn(II) domain formed by these tetracysteine motifs may be required for interaction with single-strand DNA in removal of hypernegative supercoils [ 39 ] or disruption of early recombination intermediates between inappropriately paired DNA molecules [ 40 ] .

  • These findings supported an RNA-binding prediction for YlxR and most likely a protein-protein interaction interface for YbaK.

  • Alternatively, if a protein interacts with other proteins, then differences in those partner proteins will drive changes in the regions of the protein involved in the interaction.


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