Example sentences for: inhibiting

How can you use “inhibiting” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • In another report, micro-injection of PP1 decreased extractability of pRB from nuclei, presumably by increasing dephosphorylation and increasing association with nuclear proteins thereby playing a role in G1/S transition inhibition [ 13 ] . Micro-injection of antibodies to the PP1 catalytic subunit has been shown to block cells in metaphase [ 23 ] . Since this is the time during mitosis when pRB is normally dephosphorylated [ 11 24 ] , it is tempting to speculate that prevention of pRB dephosphorylation by inhibiting PP1 activity impedes an orderly progression through mitosis, perhaps contributing towards a transformed phenotype.

  • In addition, to ensure that databases built on the bases of selectivity also possess structural information about the corresponding generic activities (binding to the NMDA or DA receptors, inhibiting both MAO isoforms), active compounds were required to have low K i (the dissociation constant of the molecule-receptor (enzyme) complex).

  • The IC 50 value was calculated as the concentration of antagonist inhibiting the 5-HT evoked response by 50%.

  • The data we present here reveal that IDO expression is an important determinant of the way in which cells interact with their extracellular environment in vitro . In particular, cell adhesion is altered dramatically by overexpressing IDO in cells which do not otherwise express it, or inhibiting IDO expression in cells in which it is naturally induced following cell passage.

  • In this study, the tumour growth inhibiting effect of ATF-BPTI gene transfer was investigated and compared to endostatin and ATF.


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