Words similar to inhibitor
Example sentences for: inhibitor
How can you use “inhibitor” in a sentence? Here are some example sentences to help you improve your vocabulary:
Given the inhibitor activity of 6b, the contribution of the oxygen in the position of the α-β bridging oxygen of 1 was examined.
For example, both EPA and isoproterenol increase the tyrosine phosphorylation of the EGFR, which appears to be required for ERK activation since the presence of kinase-deficient EGFR mutants or the kinase inhibitor, AG1478, prevents both responses.
Data were plotted as the fractional response versus the concentration of inhibitor and analysed using GraphPad software.
3], 75 mmol/l KCl, 3 mmol/l MgCl 2 , 1 mmol/l DTT,10 μmol/l dNTP [Sigma], 5 U/ml PRIME RNase Inhibitor [5 Prime ?? 3 Prime Incorporated, Boulder, CO, USA], 300 U/ml RNAguard [Pharmacia Biotech], 200 ng/ml oligo [dT] 24 [Integrated DNA Technologies Incorporated, Coralville, IA, USA], and 0.5% NP-40).
Rab proteins comprise a large family of Ras-related GTPases that function in the anterograde and retrograde trafficking of proteins in mammalian cells [ 1 2 3 ] . Different Rab proteins reside in specific subcellular membranes or organelles, where they mediate vesicular transport between discrete donor and acceptor compartments in the endocytic or exocytic pathways [ 4 5 ] . Detailed studies of a few Rab proteins ( e.g .; Rab1, Rab5 and Rab9) have led to a general model wherein Rab proteins are presumed to cycle on and off donor and acceptor membranes in connection with changes in their guanine nucleotide state [ 6 7 8 ] . In the active GTP-bound state, Rab proteins associate with budding transport vesicles [ 9 10 11 ] and appear to participate in the assembly of membrane docking complexes [ 12 13 14 ] . Following vesicle fusion with the acceptor compartment and GTP hydrolysis, the inactive GDP-bound Rab is extracted from the membrane by a carrier protein termed guanine nucleotide dissociation inhibitor (GDI) [ 15 16 17 ] . The GTPase can then re-enter the transport cycle through nucleotide exchange promoted by a specific exchange factor at the donor vesicle membrane [ 18 19 20 ] . In addition to changes in guanine nucleotide state, the posttranslational prenylation of Rab proteins plays an important role in the cycling mechanism.
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