Example sentences for: inactivating

How can you use “inactivating” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • MG-132 is a peptide aldehyde that inhibits ubiquitin-mediated proteolysis by binding to and inactivating 20S and 26S proteasomes [ 49 62 ] . Although 1-10 μM MG-132 inhibited first polar body extrusion in rat oocytes, its activity is reversible [ 42 ] . We conducted preliminary experiments to obtain a MG-132 dose range that would transiently perturb or inhibit OM during meiosis I while enabling oocytes to complete OM following washing out of the compound.

  • Individuals with inactivating mutations of their androgen receptor (AR) (androgen insensitivity syndromes (AIS)) are phenotypically female in appearance and behavior and lack male sex accessory organs (prostate, seminal vesicles and Cowper's glands) despite the presence of testes, high levels of testosterone and a Y chromosome [ 1].

  • To determine whether the down-regulated expression of the MGMT gene is due to genetic mutations, we examined the entire coding region in 30 GCTs and found no inactivating mutations (unpublished observations).

  • Proteins, such as serine proteases and their inhibitors, could alter the quality of this highway and thus play critical roles in migratory processes [ 1 ] . Members of the serine protease inhibitor superfamily, or serpins, act by binding to and permanently inactivating their target protease(s).

  • Taken together, these results suggest that statins influence APP processing, at least in part, by modulating the isoprenoid pathway and inactivating the ROCK1 kinase.


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