Words similar to inactivating
Example sentences for: inactivating
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4-aminopyridine, at millimolar concentrations, completely inhibits K +currents conducted by heterologously expressed KCNA channels and native GC I Kur , but lacks significant effects on native GC I Ks [ 4 12 13 20 ] . Kusaka showed that antagonism of 4-AP sensitive slowly inactivating delayed rectifier K +currents suppressed both basal and luteinizing hormone (LH)-stimulated progesterone production [ 21 ] . In this report, we extend those findings by demonstrating 4-AP inhibition of follicle stimulating hormone (FSH)-stimulated progesterone production, and by elucidating the underlying mechanisms.
In the absence of a method such as this for either removing or inactivating unused OCP, nonspecific background amplification can occur [ 13 ] . Sequencing of misamplification products (data not shown, [ 14 ] ) has revealed that misamplification products produced in the absence of ligase usually consist of a short OCP-derived sequence immediately flanked by primer sequences.
Separase is needed for inactivating cohesions and enabling sister chromatid separation [ 35 36 37 ] in both fission yeast [ 38 ] and mammalian cells [ 39 ] . Although differences have been reported among species [ 40 ] and cell types [ 41 ] , it appears that the majority of cohesion is removed from mammalian chromosomes during prophase and prometaphase; whereas, a lesser amount remains at kinetochores until anaphase onset.
Three independent mouse lines carrying inactivating Pten mutations have been made [ 23, 24, 25].
Individuals with inactivating mutations of their androgen receptor (AR) (androgen insensitivity syndromes (AIS)) are phenotypically female in appearance and behavior and lack male sex accessory organs (prostate, seminal vesicles and Cowper's glands) despite the presence of testes, high levels of testosterone and a Y chromosome [ 1].
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