Example sentences for: inactivates

How can you use “inactivates” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Earlier studies identified tab2 and TAB6 as mutations in NET1 and CDC14, respectively [ 15 18 ] . Net1 detains Cdc14 in the nucleolus and inactivates it until a Tem1-dependent signal sets Cdc14 free to promote exit from mitosis [ 15 16 17 ] . The fact that both Net1 and Cdc14 are directly involved in exit from mitosis prompted us to further analyze tab mutants.

  • We also found evidence that promoter methylation inactivates gene expression in CC and exposure to methylation and/or histone deacetylase (HDAC)-inhibiting agents reactivate the gene expression.

  • Akt directly phosphorylates and inactivates the pro-apoptotic proteins ASK1, BAD, caspase 9 [ 21 22 23 24 ] . Akt also induces the expression of the anti-apoptotic Bcl-2 and c-FLIP proteins, and suppresses the cell cycle inhibitor p27 KIP [ 25 26 27 28 ] . This later effect is via the phosphorylation and inactivation of the forkhead family of transcription factors AFX, FKHR and FKHR-L1.

  • Since the pre-pulse was not sufficiently long for inactivation to reach steady-state, we are not certain whether the observed incomplete inactivation reflects a component of the γ 1 null Ca 2+current that inactivates extremely slowly or a "truly" non-inactivating component.

  • The same effects were seen when they transfected the cells with a dominant negative form of ROCK1 (which inactivates the normal ROCK1 molecules in the cell); this outcome shows that the pathway can influence APP cleavage.


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