Example sentences for: inactivated

How can you use “inactivated” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • These studies provide evidence that plant myosins bind calmodulin in the absence of Ca 2+and are active when calmodulin is bound and inactivated when the Ca 2+concentration is increased.

  • 2A), the Ca 2+current of γ 1 het and γ 1 null cells inactivated more slowly than that of control cells.

  • Individual cell types will soon be reversibly inactivated (Johns et al.

  • This glioma is deficient in PTEN and shows constitutive activation of Akt, which can be inactivated by re-introduction of PTEN [ 47 ] .

  • Nonetheless, E2F is inactivated and/or downregulated upon progression to S phase, a regulatory feature that appears critical as E2F overexpression or ectopic activation induces apoptosis both in mammalian cells and in flies [ 12 ] [ 13 ] [ 14 ] [ 15 ] . Inactivation of the DNA-binding activity of E2F-1 by the cyclin A/Cdk complex has been shown to be critical for proper S phase progression [ 16 ] . In mammalian cells, E2F-1 is also subject to proteasome-mediated degradation [ 17 ] [ 18 ] [ 19 ] and recent evidence indicates that E2F-1 degradation occurs in S phase [ 20 ] . Control of E2F-1 stability has also been linked to its association with the F-box protein Skp2 [ 20 ] but this has not been tied to a specific phase of the cell cycle.


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