Words similar to ifng-induced
Example sentences for: ifng-induced
How can you use “ifng-induced” in a sentence? Here are some example sentences to help you improve your vocabulary:
Taken together, the above results showed a strong potentiating effect of PMA on IFNg-induced HLA-DR expression in LS1034 cell line and no changes in two other poorly inducible cell lines.
It remains to be determined whether the restoration of IFNg-induced MHCII expression by PMA is unique to LS1034 cells.
Specifically, the influence of a potent PKC activator, PMA, and clinically tested drug, Bryostatin 1, on the IFNg-induced MHCII expression in several IFNg-resistant tumor cell lines was examined.
In certain types of tissues, ethanol has been shown to induce membrane translocation of PKC isoforms through activation of phospholipase A and release of diacylglycerol [ 40 ] . This mechanism, however, does not appear to be significant in our case as ethanol without PMA failed to potentiate IFNg-induced MHCII expression in LS1034 cells.
However, if clinically tested PKC agonists such as Bryostatin 1 are able to rescue the IFNg-induced MHCII expression within the tumor bed, it might be appropriate to consider them for trials to improve the clinical efficacy of cancer immunotherapy.