Words similar to ifng

Example sentences for: ifng

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When cell cultures reached 40-60% confluency (usually, on the next day), growth medium was replaced with 2 ml of fresh medium containing variable concentrations of IFNg.
A poor response of tumor cells to IFNg is in agreement with previous observations that many tumors acquire such resistance upon malignant transformation, possibly important as a mechanism of tumor escape from immune surveillance [ 29 ] . The nature of this phenomenon is complex, and multiple defects that can prevent IFNg responses in tumor lines have been described.
Another reported mechanism of IFNg resistance in tumor cells is associated with down-regulation of IFNg-receptors [ 38 ] . The relevance of this mechanism to MHCII inducibility was recently supported by the evidence that PMA is able to enhance IFNg-dependent MHCII expression in THP-1 human leukemia cells through the up-regulation of IFNg receptors [ 19 ] . In our experiments, however, the incubation of LS1034 cells with PMA and ethanol did not lead to any changes in IFNgR expression as determined by flow cytometry (Figure 4).
Four dose levels of IFNg combined with 5 dose levels of PMA and 2 dose levels of ethanol generated 40 groups and the design was replicated 4 times.
The results demonstrated a substantial increase in MHCII expression in LS1034 cell line following combined incubation with PMA and IFNg (Figure 2).