Words similar to hsps
Example sentences for: hsps
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Homologs were identified as HSPs with an expected value < 10 -20and ≥ 30% identity over 100 amino acids.
Immunofluorescence with antibodies to surface-labeled chaperones/HSPs
Calnexin, Calreticulin, GRP94 (glycoprotein 96) and GRP78 (BiP) have been identified on the cell surface of immature thymocytes [ 16 17 ] . Cell surface expression of GRP94 is found in lymphocytes and lymphoid-like cells from several vertebrate species and is phylogenetically conserved [ 18 ] . Calnexin has been found on the surface of pro-B cells [ 19 ] , as well as in a variety of mammalian culture cells [ 20 ] and a number of HSPs are found expressed on the cell surface in human and murine tumor cells [ 21 22 23 24 ] . Calreticulin, GRP78 and PDI were described on the plasma membrane of different cell types [ 25 26 27 28 ] ; GRP78, GRP94, and PDI, have been found on the surface of rat exocrine pancreatic cells [ 29 30 ] , and GRP78 cell surface expression was recently shown in human endothelial cells [ 31 ] .
All complete CYTH domain sequences were aligned using the T_Coffee program, and this alignment was further refined based on the PSI-BLAST HSPs, conserved motifs detected in the Gibbs sampling procedure and predicted secondary structure for the individual groups (Fig.
Although HSPs were originally identified as a family of proteins that are upregulated in response to cell stress, most are also endogenously expressed under physiological conditions.