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Example sentences for: hspgs

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Another example of this closely parallels our findings [ 38 ] . The adhesion of Jurkat T cells to thrombospondin-1 has been shown to require the cooperation of three classes of receptors; β1 integrins, CD47 and HSPGs [ 38 ] . Adhesion of the Jurkat T cells to thrombospondin-1 stimulates ERK1/2 activation and the binding of HSPGs to thrombospondin-1 is required for this signaling.
Our results demonstrate that both integrins and cell surface HSPGs are required for robust ERK 1/2 activation when cells adhere to III1-C.
10, most of the 46 kDa and 70 kDa HSPGs bound to III1-C Sepharose but not to III 11-C Sepharose.
In addition, the presence of heparin in the lysate inhibited the 46 kDa and 70 kDa HSPGs from binding to the III1-C column (Fig.
Heparitinase and chondroitinase ABC treatment of the 35SO 4 labeled samples revealed that the 450 kDa proteoglycan was composed mostly of HSPGs (Fig.