Words similar to hspl

Example sentences for: hspl

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Overall, these data show the utility of using the HSPL peptides for subdividing protein:protein interacting domains and for defining unique novel biological activities not observed through the natural ligand/receptor interaction.
This technology has also been successfully used for known protein targets, such as the insulin receptor [ 3 ] and TNF-β [ 38 ] as well as non-protein targets such as disease-specific RNAs [ 38 ] . We have also shown that the HSPL libraries identify hotspots on novel genes of unknown function and identify functional interaction pathways (manuscript in preparation).
By panning our peptide libraries against the TNFR2, we isolated four HSPL peptides binding specifically to human TNFR2 that allow the subdivision of the receptor into a minimum of at least three independent hotspots involved in its interaction with TNFα.
RB prepared the primary and secondary HSPL libraries.