Example sentences for: hsv

How can you use “hsv” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The control viruses, HSV-2 6757 and HSV-1 PAA r5, demonstrated mutator or antimutator phenotypes, respectively, in the tk mutagenesis assay, but not in the non-HSV DNA mutagenesis assay.

  • Drug-independent mutation frequency using non-HSV DNA

  • Reiterated sequence elements are often observed to form an unwound S1 nuclease-sensitive DNA conformation, termed anisomorphic or left-handed DNA, when present in negatively supercoiled plasmids [ 22 24 ] . Nuclease-sensitive secondary structures within the HSV origin of replication are believed to be recognized by the viral origin binding protein, and mutations that reduce this complex formation in vitro also reduce viral replication, thereby indicating that localized torsional strain may occur during viral DNA replication [ 1 ] . The

  • [ 9 ] demonstrated sequential HSV inoculation from mouse to mouse receiving sub-optimal ACV therapy led to the selection and amplification of resistant virus in vivo.

  • To assess the direct contribution of polymerases from virus types 1 and 2 to mutation frequency, recombinant HSV expressing a type 2 Pol within a type 1 viral genome were generated by marker transfer and examined along with a panel of other HSV isolates in two mutagenesis assays.


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