Words similar to hsv
Example sentences for: hsv
How can you use “hsv” in a sentence? Here are some example sentences to help you improve your vocabulary:
The targeting vector also contains the HSV TK gene to allow for negative selection of non-recombinants.
The replicative polymerase of herpes simplex virus (HSV) is comprised of catalytic (Pol) and processivity subunits (UL42) [ 9 11 ] . HSV Pol is responsible, in concert with other viral proteins, for regulating the fidelity of DNA replication by selecting the correct nucleotides for incorporation and by proofreading or editing mispaired nucleotides [ 20 ] . The Pol subunit contains intrinsic 3'-5' exonuclease activity [ 14 15 16 ] and the N-terminal region of the polypeptide encoding this function is highly conserved in other polymerases, containing three segments referred to as Exo motifs [ 3 26 ] .
The control expression plasmid, pEVRF0, contains the human CMV enhancer/promoter, the translation initiation from HSV thymidine kinase, splicing and polyadenylation signals from the rabbit β-globin gene, and the SV40 origin of replication in the pSP65 bacterial plasmid.
Despite ongoing, albeit reduced, viral replication in the animals, selection of resistant HSV with the prodrugs proved difficult.
To eliminate any contribution of drug selection or tk gene template on the spontaneous mutation frequency in the tk mutagenesis assay, non drug-selected HSV replication-dependent mutations within an unrelated prokaryotic gene were measured using a LacZ shuttle plasmid assay.
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