Example sentences for: hsv

How can you use “hsv” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Female BALB/c mice (18-20 g; Charles River, Raleigh, NC) were infected intradermally in both ear pinnae with 20 μl of virus suspension containing 10 5PFU of HSV as previously described [ 1 ] . The same viral challenge was used for each subsequent in vivo passage.

  • This mutation has also been detected in clinical isolates from patients immunocompromised [ 12 ] or with AIDS [ 19 ] as well as resistant HSV selected in tissue culture [ 15 18 ] . Interestingly, this mutation was present in ACV rclinical isolates obtained during reactivation in the absence of drug pressure, as well as in ACV rstrains which evolved during ACV therapy and were followed by ACV-susceptible isolates at the next reactivation [ 19 ] .

  • The targeting vector also contains the HSV TK gene to allow for negative selection of non-recombinants.

  • In this study, we have extended the findings of previous work [ 13 ] by using pol -recombinant viruses to examine mutation frequency in HSV.

  • The tk mutagenesis assay has been utilized by ourselves and others [ 10 13 ] to determine both frequency and spectrum of mutations in the HSV tk gene following selection for drug resistance.


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