Words similar to hsv
Example sentences for: hsv
How can you use “hsv” in a sentence? Here are some example sentences to help you improve your vocabulary:
Viral populations are naturally heterogeneous; there are approximately 6 to 8 TK deficient variants per 10 4plaque-forming units (PFU) of HSV-1 (laboratory strains and clinical isolates) that have never been exposed to antiviral selection [ 6 13 15 17 ] . Resistance to nucleoside inhibitors of HSV arises readily in tissue culture probably by selection of pre-existing mutants [ 10 13 18 ] . Moreover, Field et al.
HSV-2 6757, although not 6757PR, conferred a slightly higher proportion of mutations in non-HSV DNA in the plasmid assay, than wild type HSV-1 and HSV-2, consistent with a mutator phenotype.
The control expression plasmid, pEVRF0, contains the human CMV enhancer/promoter, the translation initiation from HSV thymidine kinase, splicing and polyadenylation signals from the rabbit β-globin gene, and the SV40 origin of replication in the pSP65 bacterial plasmid.
HSV with TK mutations may impair activation of these drugs and confer a drug-resistant phenotype.
The tk mutagenesis assay has been utilized by ourselves and others [ 10 13 ] to determine both frequency and spectrum of mutations in the HSV tk gene following selection for drug resistance.