Words similar to hsv
Example sentences for: hsv
How can you use “hsv” in a sentence? Here are some example sentences to help you improve your vocabulary:
Viral populations are naturally heterogeneous; there are approximately 6 to 8 TK deficient variants per 10 4plaque-forming units (PFU) of HSV-1 (laboratory strains and clinical isolates) that have never been exposed to antiviral selection [ 6 13 15 17 ] . Resistance to nucleoside inhibitors of HSV arises readily in tissue culture probably by selection of pre-existing mutants [ 10 13 18 ] . Moreover, Field et al.
To eliminate any contribution of drug selection or tk gene template on the spontaneous mutation frequency in the tk mutagenesis assay, non drug-selected HSV replication-dependent mutations within an unrelated prokaryotic gene were measured using a LacZ shuttle plasmid assay.
The vector pRL-TK (Promega), expressing the Renilla luciferase enzyme from the HSV thymidine kinase (TK) promoter, was included as an uninduced constitutively expressed internal control.
The presence of an antimutator phenotype with this viral polymerase in the tk mutagenesis assay was not apparent when using the non-HSV DNA mutagenesis assay, and therefore phenotype-labelling may be dependent upon both the assay method and/or the target gene.
This assay employed transfection of a plasmid containing the 230 bp SmaI fragment of ori s , the HSV origin of replication, and a LacZ reporter gene, into Vero cells.