Example sentences for: granulomatous

How can you use “granulomatous” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Although Still's disease can rarely lead to hepatic involvement with cholestatic hepatitis, the prior history of rheumatoid factor seropositivity and a low serum ferritin level made this diagnosis unlikely [ 21 ] . Granulomatous hepatitis with marked elevations in serum alkaline phosphatase and granulomas on liver biopsy have been reported in patients with SSZ hepatotoxicity [ 22 23 24 ] . Although liver tissue was not obtained in our patient, the predominance of serum alkaline phosphatase and bilirubin level elevations and the presence of granulomas in other tissues suggest that she probably had granulomatous hepatitis.

  • To our knowledge, only one other case of a systemic granulomatous reaction to SSZ has been reported which improved within 24 hours of SSZ discontinuation [ 18 ] . In other cases of granulomatous drug reactions, multi-organ involvement with fevers and eosinophilia have been reported [ 19 20 ] .

  • In recent years Burkholderia cepacia has become the second leading cause of death in patients with chronic granulomatous disease (CGD).

  • Lastly, Crohn's disease or ulcerative colitis with extraintestinal manifestations was a possibility with her severe iron deficiency anemia, diarrhea, and granulomatous enteritis.

  • Seizures have previously been reported in patients receiving SSZ, often in the setting of other clinical manifestations of toxicity [ 31 41 42 ] . Although a brain biopsy would be needed to prove our hypotheses, there is a precedent for other systemic granulomatous disorders such as sarcoidosis leading to CNS granuloma formation and seizures [ 43 44 ] . Fortunately, this patient has remained stable with no evidence of a progressive neurological disorder 7 months after presentation.


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