Words similar to granulomatous
Example sentences for: granulomatous
How can you use “granulomatous” in a sentence? Here are some example sentences to help you improve your vocabulary:
Although rheumatology patients may be at increased risk of SSZ toxicity compared to IBD patients, there are no reliable laboratory or clinical predictors of SSZ toxicity [ 45 ] . Therefore, practicing physicians should be aware of the potential for severe, unexplained granulomatous reactions to SSZ that can mimic other infectious, malignant, and autoimmune conditions.
The phenotype of the Blau syndrome resembles another multisystem granulomatous disorder, Crohn's disease (MIM 266600), and another autoimmune disease, psoriasis (MIM 177900).
To our knowledge, only one other case of a systemic granulomatous reaction to SSZ has been reported which improved within 24 hours of SSZ discontinuation [ 18 ] . In other cases of granulomatous drug reactions, multi-organ involvement with fevers and eosinophilia have been reported [ 19 20 ] .
Lastly, Crohn's disease or ulcerative colitis with extraintestinal manifestations was a possibility with her severe iron deficiency anemia, diarrhea, and granulomatous enteritis.
Sulfasalazine (SSZ) is a widely used and highly effective anti-inflammatory agent in the treatment of Crohn's disease and ulcerative colitis [ 1 2 3 ] . SSZ is also being used with increasing frequency in the treatment of various rheumatolgical disorders [ 4 5 6 7 ] . SSZ is preferred over other agents such as gold and penicillamine in rheumatology patients due to its more favorable side effect profile [ 8 9 10 ] . Nonetheless, rash, fever, and dyspepsia occur in 3% to 20% of treated patients [ 7 11 12 ] . These reactions are usually dose dependent and improve with dose reduction or discontinuation [ 7 12 ] . However, more serious but less common side effects have also been reported [ 13 14 15 16 17 18 19 ] . We now report a severe systemic reaction to SSZ in a 21-year-old female with rheumatoid arthritis characterized by granulomatous infiltration of the bone marrow, colon and small bowel as well as cholestatic hepatitis and seizures.
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