Example sentences for: granulation

How can you use “granulation” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Besides fibroblasts, granulation tissue consists of macrophages, blood vessels, and extracellular matrix (ECM) produced by fibroblasts.

  • Upon injury, they are activated by the cytokines and growth factors released during the coagulation process to produce chemokines and additional cytokines and growth factors that are important in setting up the cascade of events that lead to granulation tissue formation.

  • This is the first demonstration that treatment of wounds with a pro-inflammatory and angiogenic chemokine accelerates development of the granulation tissue during healing by stimulating the precocious deposition of ECM molecules that are critical for proper healing.

  • TGFβ1 also supports the differentiation of fibroblasts into myofibroblasts, which are a major constituent of the granulation tissue [ 23 24 ] . The process depends upon the deformability of the ECM [ 17 25 ] and is mediated by the ED-A splice variant of fibronectin [ 26 27 ] . ED-A fibronectin is expressed in the initial stages of wound healing and along with collagen I is positively regulated by TGFβ1 [ 26 ] .

  • cCAF (and maybe other chemokines), on the other hand, may have a subtler, more controlled effect, promoting the earlier appearance of a normal granulation tissue without leading to excess matrix accumulation and scarring.


How many words do you know? Try our free vocabulary size test!


Search

Search for example sentences

Loading Loading...
Quantcast