Words similar to granulation
Example sentences for: granulation
How can you use “granulation” in a sentence? Here are some example sentences to help you improve your vocabulary:
However, no granulation tissue formation was visible at this stage of healing in either wild-type or SPARC-null mice (results not shown).
At this stage, the wounds are closed and are beginning to remodel in the cCAF-treated wounds while the granulation tissue in the control wings is still maturing.
Upon injury, they are activated by the cytokines and growth factors released during the coagulation process to produce chemokines and additional cytokines and growth factors that are important in setting up the cascade of events that lead to granulation tissue formation.
[ 1 2 ] ). Reepithelialization and granulation tissue formation in turn involve proliferation and migration of cells from the wound edge to fill the wound site.
The first evidence that chemokines are associated with wound healing in vivo was reported in 1990 using the chemokine cCAF (chicken Chemotactic and Angiogenic Factor; the product of the 9E3 gene), a CXC chemokine that is now known to be the ortologue for human IL-8 [ 9 ] . cCAF is expressed to high levels very shortly after wounding and during the first 24-48 hours after injury, and remains elevated for at least 16 days after wounding [ 6 10 ] . It is primarily expressed by the fibroblasts of the granulation tissue, especially where interstitial collagen (Coll) is abundant, but the levels are also high in the endothelial cells of the microvessels, in the healing epidermis and in the connective tissue beneath the skin [ 6 11 ] . In the chicken chorioallantoic membrane (CAM) assay, low concentration of cCAF results in chemotaxis of monocyte/macrophages and lymphocytes and the formation of a granulation-like tissue beneath the chemokine-containing pellet [ 3 ] . After four days of exposure to this chemokine, the ectoderm of the CAMs becomes thickened and the amount of fibrillar collagen in the tissue is markedly increased, strongly suggesting that cCAF is able to initiate some of the primary events that lead to granulation tissue formation [ 3 ] .
Loading...