Example sentences for: granulation

How can you use “granulation” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • In adults, TN, specifically TN C, is present almost exclusively in the granulation tissue of healing wounds [ 12 24 ] . In addition to providing a matrix for rapid migration of cells during wound repair, TN supports differentiation of fibroblasts into myofibroblasts [ 25 ] , which then produce more TN than do normal fibroblasts [ 15 18 ] . Because cCAF stimulates fibroblasts to differentiate into myofibroblasts, we tested the possibility that this chemokine also affects TN production.

  • Three-dimensional (3D) collagen gel culture has been used as an in vitro model of in vivo tissue contraction, a common feature of fibrosis, as well as the resolution of granulation tissue that characterizes repair [ 1, 2].

  • Thus, we conclude that SPARC deficiency compromises granulation tissue formation that involves fibroblast ingrowth and ECM protein deposition.

  • Shortly after injury, these small cytokines are primarily produced by fibroblasts, chemoattract leukocytes and activate their integrins causing them to adhere strongly to the endothelial cells as a prelude to their migration through the blood vessel wall to the underlying tissue and towards the source of the chemokine [ 5 ] . In addition to these functions during the early stages of wound healing, these small cytokines are also known to be involved in re-epithelialization, angiogenesis and granulation tissue development [ 3 6 7 8 ] , processes that are critical for proper healing.

  • Wound healing involves reepithelialization, granulation tissue formation and contraction (reviewed in refs.


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