Example sentences for: granzyme

How can you use “granzyme” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Northern blot analysis (using the same fragment as probe) did not discriminate between the genes for granzyme B versus granzyme H (Fig.

  • However, by using gene-specific probes in an RNase protection assay, we were able to demonstrate the over-expression of granzyme B and granzyme H separately in leukemic LGL cells (Fig.

  • A probe set was generated by Affymetrix using the similar sequence information (GB Accession No.M28879) and according to oligonucleotide array, granzyme B was shown to be up-regulated (fold change 21.

  • However, using gene-specific probes in an RNase protection assay, we were able to distinctly identify the over-expression of both granzyme B and H in leukemic LGL cells (Fig.

  • Maximum enhancement of NK mediated cytotoxicity was observed with a combination of IL-12 and IL-2, the effect of the two cytokines together being additive [ 2 ] . Another study revealed that cytokine stimulated NK cells use both granzyme/Fas ligand pathways of apoptotic induction to mediate cytotoxicity [ 3 ] and it was found that IL-2 and IL-12 both increase induction in mRNA coding for perforin/ granzymes A and B [ 4 ] . Hence the importance of both these cytokines in enhancing cytotoxicity cannot be overlooked.


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