Words similar to granzyme

Example sentences for: granzyme

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Maximum enhancement of NK mediated cytotoxicity was observed with a combination of IL-12 and IL-2, the effect of the two cytokines together being additive [ 2 ] . Another study revealed that cytokine stimulated NK cells use both granzyme/Fas ligand pathways of apoptotic induction to mediate cytotoxicity [ 3 ] and it was found that IL-2 and IL-12 both increase induction in mRNA coding for perforin/ granzymes A and B [ 4 ] . Hence the importance of both these cytokines in enhancing cytotoxicity cannot be overlooked.
In normal PBMC only trace amounts of both genes were identified, but after activation by PHA and IL2 only granzyme B was up-regulated.
M 57888) spotted on the cDNA microarray as granzyme B was not able to distinguish between granzyme B and H (Fig.
A probe set was generated by Affymetrix using the similar sequence information (GB Accession No.M28879) and according to oligonucleotide array, granzyme B was shown to be up-regulated (fold change 21.
However, by using gene-specific probes in an RNase protection assay, we were able to demonstrate the over-expression of granzyme B and granzyme H separately in leukemic LGL cells (Fig.