Words similar to granule
Example sentences for: granule
How can you use “granule” in a sentence? Here are some example sentences to help you improve your vocabulary:
The cytotoxicity of domoic acid to neuronal tissue in vitro has been investigated over a wide range of concentrations, namely at 10 μM with primary cultures of cerebellar neurons [ 30 31 ] as well as hippocampal slices [ 33 ] , at 100 μM with cultured prenatal rat hippocampal neurons [ 29 ] and at 20 mM with rat lumbar spinal interneurons [ 28 ] . In order to determine a concentration of domoic acid for our in vitro studies that was toxic to cerebellar granule cells after a short-term exposure in our experimental conditions, we completed a viability study using the WST-1 method.
As has been previously reported, in non-transgenic animals we detected nuclear β-catenin only in the thalamus and other deep grey matter structures [ 31 ] . In transgenic lines expressing mutant, stabilized protein, immunohistochemical analysis revealed nuclear β-catenin in both internal granule layer (IGL) and molecular layer neurons of the cerebellum.
In these P0 animals we failed to identify nuclear β-catenin in the proliferative cells of the cerebellar external granule cell layer or in periventricular neuroblasts.
Additional insights have been gained by utilizing cultures of postnatal cerebellar neuron precursors [ 2 ] . These studies have shown that Hh patterns the cerebellum by promoting proliferation of the granule neuron precursors.
A recent report demonstrates a 25% range of granule cell packing density among 35 BXD recombinant inbred lines [ 41], a finding supporting the notion that packing density varies significantly among mouse strains.
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