Words similar to granulocytes
Example sentences for: granulocytes
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IL-8 is a potent chemotactic factor for granulocytes and T lymphocytes, and is found in HIV-infected individuals.
Following continuous exposure to 1 μM retinoic acid for 96 hours, almost 40% of cells have differentiated to granulocytes, as seen by the positive NBT staining.
This decrease is consistent with data suggesting that the reduction in leukocytes results from a decrease in granulocytes and monocytes as they become activated, migrating and adhering to vascular endothelium [ 44 ] . This drop in cell numbers was followed by an increase in all leukocyte populations, beginning at 12 hours and continuing through the 72-hour time point.
Our results suggest an intriguing possibility that regulation of retinoic acid formation in the HL-60 cells, and the subsequent terminal differentiation to granulocytes, could be mediated by one enzymatic acitivy, e.g. a CYP-mediated oxidation of retinal, whereas regulation of retinoic acid formation in the hematopoietic stem cells, and the subsequent maintenance of the self-renewal capacity of the hematopoietic stem cells, is mediated by ALDH1A1 oxidation of retinal (Figure 3).
Scorpion venom when injected exerts a strong inflammatory response [ 11 ] . Many plant species used against stings contain compounds with antiinflammatory properties, flavonoids (rutin, hesperidin, quercetin), coumarins (bergapten), coumestans (wedelolactone), triterpenes, sterols and saponins [ 38 11 ] . The mechanism of action of the flavonoids is based on the inhibition of enzymatic steps in the arachidonic acid cascade [ 38 ] . Plant compounds that are immunostimulants at very low doses are some alkaloids, quinones, isobutylamides, phenolcarboxylic acid esters and terpenoids [ 39 ] . Other plant compounds with immunostimulatory effects are sesquiterpene lactones [ 40 ] . Many polysaccharides and glycoproteins enhance the unspecific immune system by activating the phagocytotic activity of granulocytes and macrophages, or by inducing cytokine production or influencing complement factors [ 39 ] .
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