Words similar to granulocytes
Example sentences for: granulocytes
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The stem cell population must be exquisitely regulated to ensure sufficient self-renewal as well as commitment to progenitor cells which can give rise to mature erythrocytes, platelets, lymphocytes, granulocytes, and macrophages.
Our results suggest an intriguing possibility that regulation of retinoic acid formation in the HL-60 cells, and the subsequent terminal differentiation to granulocytes, could be mediated by one enzymatic acitivy, e.g. a CYP-mediated oxidation of retinal, whereas regulation of retinoic acid formation in the hematopoietic stem cells, and the subsequent maintenance of the self-renewal capacity of the hematopoietic stem cells, is mediated by ALDH1A1 oxidation of retinal (Figure 3).
Scorpion venom when injected exerts a strong inflammatory response [ 11 ] . Many plant species used against stings contain compounds with antiinflammatory properties, flavonoids (rutin, hesperidin, quercetin), coumarins (bergapten), coumestans (wedelolactone), triterpenes, sterols and saponins [ 38 11 ] . The mechanism of action of the flavonoids is based on the inhibition of enzymatic steps in the arachidonic acid cascade [ 38 ] . Plant compounds that are immunostimulants at very low doses are some alkaloids, quinones, isobutylamides, phenolcarboxylic acid esters and terpenoids [ 39 ] . Other plant compounds with immunostimulatory effects are sesquiterpene lactones [ 40 ] . Many polysaccharides and glycoproteins enhance the unspecific immune system by activating the phagocytotic activity of granulocytes and macrophages, or by inducing cytokine production or influencing complement factors [ 39 ] .
For preparation of purified T cells (CD4 +and CD8 +) free of macrophages, granulocytes, B cells, and NK cells, the PBMC (1 × 10 7cells) were centrifuged, and diluted to 200 ul with 0.1% BSA in PBS.
Under in vitro conditions, it has been shown that ibuprofen stabilizes lyszomal membranes, restrains the secretion of lysozomal enzymes from granulocytes, and prevents the aggregation of platelets as well as the immigration of leukocytes [ 1 2 3 4 5 ] .
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