Words similar to granulosa
Example sentences for: granulosa
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In other words, selective pick up of CG through the surface LHR expression in granulosa lutein cells during the luteal phase after conception appears not to be required if the circulating CG is very high.
Within this basic quartet are many other cell types such as the ovary surface epithelium and blood vessels in addition to the classic subtypes of granulosa (membrana, periantral, cumulus, and corona radiata), theca (interna and externa), and luteal cells (granulosa and theca lutein).
6D), a feature also detected in immature granulosa cells (see above).
In granulosa cells, it has previously been shown that the level of N-terminally truncated USF2 is regulated by cAMP.
C/EBP is previously reported to be an important accessory factor for transactivation by several other transcription factors [ 26 ] . C/EBPβ was shown to transactivate the α1-acid glycoprotein gene promoter even when mutated in the DNA-binding domain, and this activation appeared to depend on protein-protein interaction with glucocorticoid receptor through the leucine zipper region [ 27 ] . Recently, a conserved domain in C/EBPα and C/EBPβ was shown to mediate cAMP responsiveness, strengthening the fact that C/EBP may be characterized as a cAMP-responsive nuclear regulator [ 28 29 ] . On the COX-2 promoter in granulosa cells, cAMP-mediated regulation was shown to be mediated primarily by an E-box that bind USF1 and USF2 isoforms in a manner resembling the RIIβ E-box in Sertoli cells [ 30 ] . Transactivation of the COX-2 gene in skin carcinoma cells is highly dependent on this E-box together with a C/EBP binding site that bind C/EBPβ and C/EBPδ [ 31 ] . These data strengthens a model of formation of a cAMP-responsive unit (CRU) containing USF and C/EBP.
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