Example sentences for: granulosa

How can you use “granulosa” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • We have shown previously that antagonism of the slowly activating non-inactivating granulosa K +current (I Ks ) enhances basal progesterone production by depolarizing membrane potential and thus enhancing calcium influx via pimozide-sensitive Ca 2+channels [ 18 ] . In contrast, Kusaka [ 21 ] showed that antagonism of 4-AP sensitive slowly inactivating delayed rectifier K +currents suppressed both basal and LH-stimulated progesterone production.

  • Early luteal development (fresh CL) was associated with very strong cytoplasmic LHR immunostaining of granulosa lutein cells migrating into the follicular cavity (gl, Fig.

  • Voltage-gated K +currents with distinct electrophysiological and pharmacological properties are present in granulosa cells (GC), and modulate resting membrane potential [ 4 12 13 16 17 ] . Furthermore, selective antagonism of GC K +channels with distinct molecular correlates, electrophysiological properties and expression patterns can influence differentially GC proliferation, steroidogenic capability, and apoptosis [ 17 18 ] . Our laboratory has previously identified two distinct delayed rectifier K +currents in pig GC: a slow current (I Ks ) associated with channels formed by co-assembly of KCNQ1 pore-forming and KCNE1 accessory proteins, and an ultra-rapid current (I Kur ) formed by co-assembly of KCNA pore-forming and KCNAB accessory proteins [ 4 ] . Moreover, we have shown that selective block of I Ks enhances basal progesterone synthesis, while complete block of both I Ks and I Kur accelerates apoptosis [ 18 ] .

  • In granulosa cells, it has previously been shown that the level of N-terminally truncated USF2 is regulated by cAMP.

  • The adult mammalian ovary is a complex tissue composed of four fundamental cell types: the oocytes, granulosa, interstitial, and corpora luteal cells.


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