Words similar to dsrna

Example sentences for: dsrna

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This is perhaps at odds with the nonspecific activity of Dicer, which efficiently processes virtually every input dsRNA ever tested in RNAi assays.
Thus, a reduction in human RNase III levels in vivo causes the accumulation of specific rRNA processing intermediates [ 18 ] . Consistent with this functional role, human RNase III localizes to the nucleolus in a cell-cycle-dependent manner [ 18 ] . A truncated form of human RNase III has been purified and shown to cleave dsRNA in vitro [ 18 ] . However, little else is known of the functional roles or the mechanistic features of this enzyme.
In the mutant dsRNA (for P), the lowercase a-u base pair was changed to g-c (see Results).
The negative control luciferase RNA was the same as the double-stranded GL3 RNA described previously [ 17 ] . The RNAs were annealed in vitro to form double-stranded RNA (dsRNA) [ 18 ] and electroporation was carried out essentially as described [ 32 ] . In brief, 3 μg dsRNA in 800 μl of incomplete cytomix [ 32 ] was added to infected RBC (at 10-15% parasitemia), and electroporation was performed using a Bio-Rad Gene Pulsar unit at settings of 200 Ω, 2 kV, and 25 μF.
The dsRNA was injected at a concentration of 25 μg/ml.