Words similar to dsrna

Example sentences for: dsrna

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As mentioned before, the N-encapsidated genome-length RNAs are indeed extremely resistant to nucleases, to the extent that formation of such nuclease-resistant RNA products is in fact considered a defining criterion for viral replication in vitro and in vivo [ 32 ] . While the resistance of the viral genomic RNA to dsRNA has important ramifications for antiviral therapy, it is also clear that the dsRNA approach cannot be used against cis -acting NNR viral genomic sequences such as the intergenic regions, for which the cDNA-based approach will continue to be the method of choice [ 16 ] . It is obvious that a creative combination of the two techniques will lead to exciting possibilities in the reverse genetics of RNA viruses and in the antiviral regimen.
systems demonstrated that 21–23 nucleotide ‘short interfering'RNAs (siRNAs), derived from cutting longer dsRNA, can guide mRNA cleavage (Zamore et al.
First, to test the effectiveness of the anti-F dsRNA intracellularly, we probed the infected cell monolayer with anti-F antibody by indirect immunofluorescence (Fig.
Expression of inverted-repeat constructs, where the transcript is expected to fold into a dsRNA hairpin, has been shown to be an efficient initiator of RNAi [ 13, 14, 15].
Transfection by inhibitory dsRNA