Words similar to dsh
Example sentences for: dsh
How can you use “dsh” in a sentence? Here are some example sentences to help you improve your vocabulary:
Therefore, the interaction between DFz2 and Dsh does not depend solely on the carboxyterminus of DFz2.
If the carboxyterminus of LRP6 can interact with Axin independently of DFz2 and Dsh, it might reduce the cytoplasmic level of Axin and help stabilize β-catenin.
The secreted glycoproteins in the Wnt/Wingless (Wg) family serve diverse functions in developmental processes, ranging from cell fate specification and cell proliferation to cell migration and cell polarity [ 1 2 ] , and deregulation of the Wnt signaling pathway can lead to cancer [ 3 4 ] . In a simplified model of the canonical Wnt/β-catenin signaling pathway, the binding of Wnts to their receptors activates a downstream component, Dishevelled (Dsh).
As additional controls in these experiments, we showed that inhibitory RNA against Dsh, a cytoplasmic phosphoprotein believed to mediate Wg signaling via Fz receptors, blocks about 60% of signaling produced by co-transfection with Wg and DFz2 plasmids.
It is known that Dsh is a key component in transducing a Wg signal [ 23 24 25 ] . However, the mechanism by which Dsh transmits a signal to the β-catenin destruction complex is not clear.