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Example sentences for: dsrnai

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The use of dsRNAi helps to refine the nature of such interactions and their effects on downstream events in the signaling circuitry.
Signaling via LRP6ΔN, however, while dependent on Arm as expected, is not dependent on Dsh or DFz2, as judged by the use of dsRNAi (Figure 5A).
In addition, the synergistic effect of Wg and DFz2ΔC was blocked by Dsh dsRNAi (data not shown), implying that Dsh is required to transduce the signal from Wg through DFz2ΔC to β-catenin.
Moreover, we found that S2 cells treated with dsRNAi against both Arr and Dsh further impaired the Wg and DFz2 signaling activity up to 95% (Figure 2B).
Experiments with Arr dsRNAi clearly establish a requirement for endogenous Arr to generate the synergistic response to exogenous Wg plus DFz2 in S2 cells (Figure 2).