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Example sentences for: dsrnai

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Moreover, we found that S2 cells treated with dsRNAi against both Arr and Dsh further impaired the Wg and DFz2 signaling activity up to 95% (Figure 2B).
To ask whether LRP6 can replace the requirement for endogenous Arr in the synergy between Wg and DFz2, as observed earlier in Figure 2B, we again used Arr-specific dsRNAi to try to block the strong activation of signaling by Wg plus DFz2, in the presence and absence of the LRP6 constructs (Figure 5C).
Signaling via LRP6ΔN, however, while dependent on Arm as expected, is not dependent on Dsh or DFz2, as judged by the use of dsRNAi (Figure 5A).
In addition, the synergistic effect of Wg and DFz2ΔC was blocked by Dsh dsRNAi (data not shown), implying that Dsh is required to transduce the signal from Wg through DFz2ΔC to β-catenin.
8 to 16 hours after dsRNAi treatment, cells were transfected with different constructs and reporters.