Example sentences for: dsdna

How can you use “dsdna” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Spo11 protein has potential functions in addition to catalyzing dsDNA breaks.

  • The role of Spo11 (Rec12) in the initiation of meiotic recombination via catalysis of dsDNA breaks is conserved and likely universal among eukaryotes.

  • Meiotically induced, Spo11 (Rec12)-dependent double-strand DNA (dsDNA) breaks have been demonstrated in budding yeast and fission yeast [ 12 13 14 15 ] . Spo11 almost certainly catalyzes these breaks, as it shares high homology with the A subunit of Topoisomerase VI of Sulfolobus shibatae [ 16 17 ] and it becomes linked by a phosphotyrosine linkage to the 5' end of the cleaved DNA [ 18 19 20 21 ] . Spo11 homologs have been identified in a wide range of eukaryotes, and available evidence suggests that initiation of meiotic recombination via Spo11-dependent dsDNA break formation is conserved [ 22 23 24 25 ] . Our results with the fission yeast S. pombe fully support this view (see results and discussion).

  • This may suggest that the possible role of Ruv protein is making a break into dsDNA [ 33 ] .

  • This provides evidence that a dimer of Rec12/Spo11 protein, harboring two functional active sites, is required for catalysis of dsDNA breaks in each organism.


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