Words similar to downregulated

Example sentences for: downregulated

How can you use “downregulated” in a sentence? Here are some example sentences to help you improve your vocabulary:

Although this shift toward a slower isoform is not as marked as that reported in humans [ 12 13 ] , in which MHC type I is upregulated and both IIa and IIx are downregulated, there is precedent for restricted MHC adaptation in rats.
However, those investigators did not observe any difference in plasma NO metabolites in normoxic versus hypoxic rats in which aortic NOS was downregulated, but did observe a decrease in acetylcholine-stimulated NO release from aortic rings.
These results contrast with other studies concluding that the production of these cytokines was downregulated or unchanged in T cells from HIV +and aged individuals [ 21 28 29 30 31 32 37 38 ] . Reliability in our findings derives from use of flow cytometric analysis which measures de novo synthesis per cell and thus obviates numerous artifacts possibly associated with ELISA or procedures that measure mRNA synthesis.
It is downregulated during F9 cell differentiation and expression of TAF II 135 at elevated levels promotes cell growth, impairs the normal T-RA response, and induces a novel differentiation pathway.
Thus, in considering models of Ptc function based on Hh-stimulated effects it is important to consider whether the form of Smo that is being observed is the active (coupler/effector bound) signaling state, or perhaps a downregulated and inactive form.