Words similar to downregulated

Example sentences for: downregulated

How can you use “downregulated” in a sentence? Here are some example sentences to help you improve your vocabulary:

To test the possibility that nmt55/p54 nrbmay be transcriptionally downregulated in ER- tumors, we analyzed mRNA levels from a series of human breast tumors utilizing Northern blot analyses and ribonuclease protection assays.
The authors studied the expression of two p53-upregulated genes ( Cdkn1a , which encodes p21, and Mdm2 ) and one downregulated gene ( Pcna ) in p53-positive tumours after irradiation and showed responses indicative of normal p53 function.
Thus, it is interesting to speculate that IL-2 and IL-4 are downregulated in the rheumatoid synovium by some active repressor mechanism induced by the synovial microenvironment.
Although this shift toward a slower isoform is not as marked as that reported in humans [ 12 13 ] , in which MHC type I is upregulated and both IIa and IIx are downregulated, there is precedent for restricted MHC adaptation in rats.
However, TGFβ downregulated Ese-1/Esx mRNA levels faster than it upregulated Smad7 expression excluding the possibility that Smad7 mediates the TGFβ effect on Ese-1/Esx, at least at the initial phase.