Example sentences for: downregulated

How can you use “downregulated” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • As a direct consequence of SKP2 downregulation, p27 is upregulated and cyclin A is downregulated.

  • Similarly, the terms 'main pathways of carbohydrate metabolism', 'catabolic carbohydrate metabolism', and 'glycolysis' also appear as downregulated in Table 2. The MAPPFinder browser (Figure 3a) shows that 'glycolysis' is related to 'main pathways of carboyhydrate metabolism' through the hierarchical relationship between these terms.

  • Although this shift toward a slower isoform is not as marked as that reported in humans [ 12 13 ] , in which MHC type I is upregulated and both IIa and IIx are downregulated, there is precedent for restricted MHC adaptation in rats.

  • Moreover, recent work shows that in embryos NT-3 is primarily expressed in supporting cells, moving only around birth into hair cells [ 6 7 ] . In fact, the selective loss of vestibular as compared to cochlear sensory neurons (77% versus 29%; [ 3 ] ) suggests that NT-3 expression may be less downregulated in Brn3c null mutants than BDNF [ 6 8 9 ] , provided that at least some differentiation of supporting cells takes place.

  • The set of genes that are consistently misregulated in regions of frequent cytogenetic change as predicted by CGMA are shown in Table 2. Platelet-derived growth factor receptor alpha is consistently downregulated in a region of frequent cytogenetic loss and this suggests that loss of a member of this receptor gene family is important in HCC progression.


How many words do you know? Try our free vocabulary size test!


Search

Search for example sentences

Loading Loading...
Quantcast