Words similar to downregulation
Example sentences for: downregulation
How can you use “downregulation” in a sentence? Here are some example sentences to help you improve your vocabulary:
Re-administration of androgen induces transient epithelial cell proliferation, presumably mediated by proteolytic downregulation of p27, until pre-castration cell numbers have been restored [ 48 49 ] . No further proliferation ensues beyond this point, at which p27 levels are increased again, despite the continuous presence of androgen.
This may contribute to the downregulation of cyclin D1 protein and is consistent with a previous report showing an increase in cyclin D1 mRNA in cells overexpressing eIF4E [ 26 ] .
A plethora of circumstantial evidence implicates downregulation of the cyclin-dependent kinase (CDK) inhibitor p27 in prostate cancer.
We show that androgen-induced p27 upregulation is paralleled by p27 stabilization and SKP2 downregulation.
The mutant version (C1684T, Arg554 → Trp; Figure 7a) of SDHA has a normal K m and K i (for malonate) but is much more sensitive to downregulation by oxaloacetate (OAA).