Words similar to downregulation
Example sentences for: downregulation
How can you use “downregulation” in a sentence? Here are some example sentences to help you improve your vocabulary:
We therefore asked whether SKP2-mediated p27 downregulation in MIB arrested LNCaP cells was able to actually bring about CDK2 activation.
As a direct consequence of SKP2 downregulation, p27 is upregulated and cyclin A is downregulated.
These results indicate that downregulation of PLD2 activity by antisense oligomers in SN56 cells decreases not only the endogenous PLD2 activity but also the intracellular choline and ACh content.
To determine whether SKP2 downregulation is a necessary step in MIB-induced p27 upregulation, LNCaP cells were blocked with MIB for 72 h, followed by infection with Ad-SKP2 or Ad-SKP2-ΔF for various periods.
This may contribute to the downregulation of cyclin D1 protein and is consistent with a previous report showing an increase in cyclin D1 mRNA in cells overexpressing eIF4E [ 26 ] .
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