Words similar to downregulate
Example sentences for: downregulate
How can you use “downregulate” in a sentence? Here are some example sentences to help you improve your vocabulary:
To date, numerous experiments in animal models suggest RNAi can downregulate a variety of target genes effectively.
This indicates that, in flies, precursors express Delta and that those specified for neuroblast development downregulate its expression.
In accord with these results, flavopiridol treatment was recently shown to downregulate two of these anti-apoptotic proteins, MCL1 and Bag-1, and induce apoptosis in B-CLL cells treated with flavopiridol [ 29].
It is remarkable that a constitutively active form of JNK activator MKK and Smad7 are able to cooperatively downregulate TGFβ-responsive promoters [ 53 ] . It is quite possible that a Smad7/JNK synergistic interaction is involved in the TGFβ-dependent downregulation of Ese-1/Esx expression, where JNK alone might mediate the initiation of the TGFβ-induced repression.
The reduction in SCF function associated with mCul1 overexpression also correlated with a failure to downregulate E2F normally in S phase.
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