Example sentences for: downregulate

How can you use “downregulate” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The reduction in SCF function associated with mCul1 overexpression also correlated with a failure to downregulate E2F normally in S phase.

  • In accord with these results, flavopiridol treatment was recently shown to downregulate two of these anti-apoptotic proteins, MCL1 and Bag-1, and induce apoptosis in B-CLL cells treated with flavopiridol [ 29].

  • It is remarkable that a constitutively active form of JNK activator MKK and Smad7 are able to cooperatively downregulate TGFβ-responsive promoters [ 53 ] . It is quite possible that a Smad7/JNK synergistic interaction is involved in the TGFβ-dependent downregulation of Ese-1/Esx expression, where JNK alone might mediate the initiation of the TGFβ-induced repression.

  • Thus it appears that a relatively small number of genes is downregulated by stress and suggests that different kinds of stress downregulate the same genes.

  • Immunoblotting revealed that SKP2 overexpression can efficiently downregulate p27 levels in the continuous presence of MIB (Fig.


How many words do you know? Try our free vocabulary size test!


Search

Search for example sentences

Loading Loading...
Quantcast