Example sentences for: diminished

How can you use “diminished” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • And it's difficult to see how the effectiveness of the Specs for Kids approach can be diminished by the boom, even in theory.

  • High levels of OPN in breast tumor cell lines appear to correlate with a more aggressive in vivo phenotype [ 2 20 ] . Transfection of OPN expression constructs into cells producing noninvasive mammary epithelial tumors has been reported to convert them to a malignant phenotype [ 8 21 ] . Furthermore, transfection of antisense OPN constructs or OPN-targeting ribozymes into transformed tumorigenic cells can result in impaired anchorage-independent growth, as well as in diminished tumor-forming ability in vivo [ 22 23 ] . OPN is also typically overexpressed in human tumors, including breast cancer [ 15 24 ] . However, the source of OPN in primary breast tumors was originally thought to be infiltrating macrophages rather than tumor cells themselves [ 15 ] .

  • HoloAPP levels are likely limiting at one or more sorting steps in the late secretory pathway, since activated sAPP α shedding is apparently accompanied by diminished generation of sAPP β [51].

  • The staining persisted in young syncytial aggregates (y, panels E and F) but diminished in mature ST (m, panels F and G).

  • This compound diminished the hepatic mRNA expression of both c-myc and p53 significantly (Fig 3).

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