Words similar to dimerization
Example sentences for: dimerization
How can you use “dimerization” in a sentence? Here are some example sentences to help you improve your vocabulary:
In the archaeo-eukaryotic lineage, another domain, apparently derived through duplication of the dimerization domain of the DDRP α-subunit, was inserted into the C-terminal region of the β' subunit.
This isoform, however, shares the C-terminal DNA binding and dimerization domain with p35-C/EBPβ.
Crystal structures of HIV-1 RT show that p66 and p51 assume different folding patterns and tertiary structures [ 11 12 ] . It has been proposed that p66 in a monomeric form exists in a closed conformation similar to p51 [ 26 ] . Following dimerization with another molecule of p51 (or p66), it assumes an open conformation [ 11 14 15 ] . The polymerase domain of p51 is buried within its core.
This includes the characteristic features peculiar to the kinase domain of GCN2 proteins, the m1, m2, and m3 motifs of the HisRS domain, and a cluster of positively charged residues at the C-terminus that are thought to function in ribosome binding and dimerization [ 31 37 41 ] . Within the kinase domain, the Dictyostelium proteins possess an inserted sequence between the 4th and 5th kinase subdomains that is also found in this position in all known GCN2-like proteins.
It associates specifically with unduplicated centrosomes, and its phosphorylation by CDK-2/cyclin E, the trigger for centrosome duplication, is required for duplication to occur [ 17 ] . The nucleophosmin gene is also known for its fusion with the anaplastic lymphoma kinase (ALK) receptor tyrosine kinase in cases of this disease with (2;5)(p23;q35) translocations [ 18 ] . The nucleophosmin portion contributes to transformation by providing a dimerization domain, which allows activation of the fused kinase and signal transduction [ 19 ] .
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