Words similar to dimers
Example sentences for: dimers
How can you use “dimers” in a sentence? Here are some example sentences to help you improve your vocabulary:
The resulting mutant derivatives of HIV-1 RT containing insertion of six amino acids in the β7-β8 loop in either or both the subunits were analyzed for their ability to form stable dimers and other biochemical characteristics.
In the structure of the native interface dimer reported here, all three dimers in the asymmetric unit contain salt-bridges from Glu44 to Lys60, Arg73 to Asp79, Asp69 to Arg71, Glu68 to Lys67, and Asp69 to Lys67.
Our glycerol gradient sedimentation analysis had revealed that the p66 WT/p51 INSmutant does not form stable dimers, rather the p66 WTsubunit tends to self dimerize.
Based on our observations from the sedimentation analysis, we propose that the loss of DNA binding function in case of the HIV-1RT insertion mutants results from a failure to form stable dimers.
Thus, the impairment of the polymerase activity seen with these mutants carrying insertion in either both the subunits or specifically in the second subunit may be related to the inability of these mutants to form stable dimers resulting in a closed polymerase cleft.
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