Words similar to dimers

Example sentences for: dimers

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The figure also introduces two derivatives of the 'molecule' icon: a 'dimer' icon (adapted from Kohn [ 6]) to represent dimers such as cyclin D1-Cdk4 and a 'biomolecule' icon as a shorthand to represent catalytically active molecules with both 'concentration' and 'activity' properties (for example the kinases in the mitogen-to-ERK and -Akt kinase cascades).
In the structure of the native interface dimer reported here, all three dimers in the asymmetric unit contain salt-bridges from Glu44 to Lys60, Arg73 to Asp79, Asp69 to Arg71, Glu68 to Lys67, and Asp69 to Lys67.
Deletion of this loop or substitution of four amino acid residues with alanine within the β7-β8 loop of p51 severely impaired the DNA polymerase activity of the enzyme as a consequence of the inability of the enzyme to form stable dimers [ 15 ] . These findings clearly establish the absolute requirement of the β7-β8 loop of p51 for RT dimerization.
Thus, the impairment of the polymerase activity seen with these mutants carrying insertion in either both the subunits or specifically in the second subunit may be related to the inability of these mutants to form stable dimers resulting in a closed polymerase cleft.
Our glycerol gradient sedimentation analysis had revealed that the p66 WT/p51 INSmutant does not form stable dimers, rather the p66 WTsubunit tends to self dimerize.