Example sentences for: dimerized

How can you use “dimerized” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The same result was obtained when p66 INSwas dimerized with p51 having Asp→Ala mutation at amino acid position 186 (one of the catalytically crucial carboxylate triad) but having an intact β7-β8 loop.

  • Two families of small peptides binding to the human thrombopoietin receptor (TPOR) were isolated that competed with the natural ligand TPO [ 34 ] . The peptide with the highest affinity was subsequently dimerized and shown to function as a potent TPO agonist in vivo . Recently, a small, non-peptide organic molecule binding to one chain of the EPO receptor was multimerized and shown to mimic the biological activities of the EPO [ 35 ] .

  • Interestingly, when the p66 INSmutant was dimerized with the wild type p51 (p66 INS/p51 WT), the polymerase activity was restored to wild type levels.

  • Interestingly, the DNA binding affinity was restored to the wild type levels, when the mutant p66 subunit was dimerized with the wild type p51 (p66 INS/p51 WT).

  • The column was washed with 15 mL of the same buffer to remove the excess of p66 that was not dimerized with p51 bound to the IDA-sepharose column.


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