Example sentences for: dephosphorylation

How can you use “dephosphorylation” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The best characterized regulation of α-secretase processing typically involves protein phosphorylation via PKC [5,29] or ERKs [7] or protein dephosphorylation by protein phosphatase 1 or 2A [29].

  • For example, the stress kinase JNK1 was activated during TLK286 induced apoptosis [ 17 ] and JNK is known to be activated during apoptosis induced by a variety of stress stimuli [ 18 ] . However, in HL60/TLK286 resistant cells, we observed an overexpression of two phosphatases PP2 (AA599092) and MKP5 (AA056608) involved in JNK dephosphorylation and inactivation (Table 2).

  • Given the reversible nature of most forms of thiol oxidation, it has been suggested that thiol modifications can play roles in signal transduction that are similar to protein phosphorylation/dephosphorylation (Sitia and Molteni 2004).

  • SAHA treatment resulted in G1 cell growth arrest in TM10 and TM2H cell lines, concomitant with the profound increase in dephosphorylation of the three pRb pocket proteins.

  • Moreover, in the absence of stable tyrosine phosphorylation as seen in the Src kinase inactive fusions, v-crk could either induce their phosphorylation, or protect transiently phosphorylated YDXP motifs from dephosphorylation through yet unknown mechanisms.


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