Words similar to dephosphorylation
Example sentences for: dephosphorylation
How can you use “dephosphorylation” in a sentence? Here are some example sentences to help you improve your vocabulary:
The best characterized regulation of α-secretase processing typically involves protein phosphorylation via PKC [5,29] or ERKs [7] or protein dephosphorylation by protein phosphatase 1 or 2A [29].
The assembly of myosin II monomers into filaments is regulated by phosphorylation of its heavy chains at three threonine residues at the C-terminus of the tail [ 9 10 ] . Dephosphorylation of these threonines is a prerequisite of filament assembly, as confirmed by the phenotypes of a 3xAsp mutant, in which the three threonines are replaced by three aspartate residues (mimicking the phosphorylated state) [ 11 ] . In vitro the 3xAsp myosin II is severely impaired for filament assembly, and in vivo 3xAsp myosin II fails to assemble or localize to the cortical cytoskeleton.
Given the reversible nature of most forms of thiol oxidation, it has been suggested that thiol modifications can play roles in signal transduction that are similar to protein phosphorylation/dephosphorylation (Sitia and Molteni 2004).
Experiments reveal that treatment with rapamycin leads to dephosphorylation of Ure2p, corroborating this low angle [ 4, 21].
Such observations suggest that PP5 may act as a co-chaperone for hsp90 and raise the possibility that protein dephosphorylation may play an important regulatory role in protein folding [ 33 34 ] . Interestingly, recent studies have identified a few residues of mammalian PP5 critically important for its interaction with hsp90 [ 34 ] . As marked on the human PP5 TPR (underlined in Fig.
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