Example sentences for: dephosphorylation

How can you use “dephosphorylation” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Moreover, in the absence of stable tyrosine phosphorylation as seen in the Src kinase inactive fusions, v-crk could either induce their phosphorylation, or protect transiently phosphorylated YDXP motifs from dephosphorylation through yet unknown mechanisms.

  • The assembly of myosin II monomers into filaments is regulated by phosphorylation of its heavy chains at three threonine residues at the C-terminus of the tail [ 9 10 ] . Dephosphorylation of these threonines is a prerequisite of filament assembly, as confirmed by the phenotypes of a 3xAsp mutant, in which the three threonines are replaced by three aspartate residues (mimicking the phosphorylated state) [ 11 ] . In vitro the 3xAsp myosin II is severely impaired for filament assembly, and in vivo 3xAsp myosin II fails to assemble or localize to the cortical cytoskeleton.

  • Specifically, phosphorylated NFATp is cytoplasmic, and upon dephosphorylation NFATp accumulates in the nucleus [ 1].

  • The recombinant full length and deletion mutants of human NFATp used in the studies described here as well as the methods that we have developed will be valuable for future biochemical studies of the function of NFATp in DNA binding, transcriptional activation, phosphorylation/dephosphorylation, and nuclear association.

  • However, as seen in Figure 1, the dephosphorylation of phosphohistone by the catalytic subunit of purified PP5 from bovine brain is also potently inhibited by okadaic acid.


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