Words similar to dephosphorylation

Example sentences for: dephosphorylation

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The recombinant full length and deletion mutants of human NFATp used in the studies described here as well as the methods that we have developed will be valuable for future biochemical studies of the function of NFATp in DNA binding, transcriptional activation, phosphorylation/dephosphorylation, and nuclear association.
For example, the stress kinase JNK1 was activated during TLK286 induced apoptosis [ 17 ] and JNK is known to be activated during apoptosis induced by a variety of stress stimuli [ 18 ] . However, in HL60/TLK286 resistant cells, we observed an overexpression of two phosphatases PP2 (AA599092) and MKP5 (AA056608) involved in JNK dephosphorylation and inactivation (Table 2).
Dephosphorylation was kept to less than 10 % of the total phosphorylated substrate, and the reaction was linear with respect to enzyme concentration and time.
Specifically, phosphorylated NFATp is cytoplasmic, and upon dephosphorylation NFATp accumulates in the nucleus [ 1].
Results suggested that SAHA induced cell growth arrest through dephosphorylation of three pRb pocket proteins, which may be related to inhibition in G1/S phase cdk activities.