Words similar to cm
Example sentences for: cm
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Due to the genetic homogeneity of the Finnish population [ 36 37 38 39 40 ] the probability of identifying genetic risk factors in a complex disease such as FIA may be substantially improved [ 37 38 40 ] . In the first stage a 10 cM genome scan was performed using the Weber screening set 8 [ 32 ] and the data analyzed using both two-point and multipoint ASP linkage analysis.
A preload of 50 N was applied to a lever arm of 40 cm from the fulcrum, in the opposite direction, at the bottom end of the specimen, as described by Chiba et al [ 6 ] . Two digital goniometers, placed at the junction of the loading frame and the lever arm, measured the angular displacement at the FSU with application of the bending moment.
They are constitutively permeable to water, and also function as regulated non-selective cation channels [ 10 ] when gated by intracellular cyclic GMP [ 11 12 ] . Even though only a small proportion of the AQP1 channels that are present in the membrane appear to be available for cGMP-activation of the ionic conductance (1/56,000), model-based calculations nonetheless suggest that this contribution could be meaningful in a physiological setting [ 13 ] . Unlike transporters which move substantial amounts of substrate by design, ion channels function to change membrane potential by the net movement of relatively tiny amounts of charge (~10 picomoles per cm 2membrane to generate a change of 100 mV) [ 14 ] , hence the low proportion of active AQP1 ion channels is consistent with a functional goal of gated ionic signaling that is distinct from that of massive constitutive osmotic water permeability.
Cells were seeded into 24-well tissue culture plates at approximately 20,000 cells/cm 2, and cultures were used immediately upon reaching confluence (usually 3-4 days after seeding).
Water permeability was measured as the net fluid movement driven by an osmotic gradient across intact monolayers of adenovirus-infected MDCK cells, by methods similar to those reported previously [ 27 29 ] . Cells were seeded onto Transwell filters (Costar, 1 cm 2, 0.4 μm pore size) at a density of 1.5 × 10 5cells per well.
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