Example sentences for: cml

How can you use “cml” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Although imatinib inhibits different kinases in various diseases (BCR-ABL in CML, KIT or PDGFR-alpha in gastrointestinal stromal tumors [GISTs], and PDGFR-alpha in hypereosinophilic syndrome [HES]) (reviewed in [14]), some tumors that become refractory to treatment with imatinib appear to have analogous secondary mutations in the kinase-coding domain of the genes encoding these three enzymes.

  • Among the most abundant glucose-modified proteins detectable in the plasma of diabetic individuals are CML proteins [21], which are typically present at 1.6 to 2.3 μM concentrations in the plasma and urine of diabetic individuals [22,23].

  • Although there are many potential mechanisms for development of clinical resistance, most cases of imatinib-resistant CML are due to point mutations in the BCR-ABL kinase domain itself, including T315I [10,11].

  • Briefly, BSA with minimal CML content (CMLmin-BSA) was prepared by incubation of BSA (0.

  • The majority of patients (69%) had secondary AML transformed from either MDS (n = 10), CML (n = 5) or other myeloproliferative diseases (n = 4), or secondary to cytotoxic agents (n = 1).


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