Words similar to cml
Example sentences for: cml
How can you use “cml” in a sentence? Here are some example sentences to help you improve your vocabulary:
Gleevec has been shown to induce clinical, hematological and molecular remissions for CML patients [ 4 ] . It cross-reacts with two other important growth factor receptors containing tyrosine kinase domains, c-kit and PDGF receptors, that play important roles in growth and proliferation of a variety of cell types [ 5 ] . C-kit (also known as CD117) is frequently mutated in gastrointestinal stromal tumor (GIST), and the mutated c-kit shows higher tyrosine kinase activity.
To use physiologically relevant CML proteins in our in vitro experiments, we prepared CMLmin-BSA, characterized by glycation of approximately 30% of lysine residues [21].
Among the most abundant glucose-modified proteins detectable in the plasma of diabetic individuals are CML proteins [21], which are typically present at 1.6 to 2.3 μM concentrations in the plasma and urine of diabetic individuals [22,23].
There has been no report to link cellular ABL kinase mutation to any cancer patients except BCR-ABL in CML, although the detailed c-Abl function has not been extensively studied in lung cancer patients.
Subclones bearing this mutation could arise de novo during treatment . However, based upon analogous studies in CML, it is also possible that NSCLC subclones bearing this secondary mutation pre-exist within the primary tumor clone in individual patients, albeit at low frequency [23].