Words similar to caspases

Example sentences for: caspases

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Bcl-2 impedes the subcellular trafficking of p53, inhibits downstream adapters necessary for stimulation of the apoptotic caspases, and can act as an antioxidant [ 15 28 ] .
Three members of the IAP family ( c-IAP1, c-IAP2, NAIP ) had very short mRNA half-lives and encode anti-apoptotic proteins that act by directly binding to caspases 3, 7, and 9 [ 27].
Both cell lines produced activated caspases 8 and 9 by 1 h after treatment with equivalent levels at 3 h.
This leaves the possibility that conjugated bile acids may activate the apoptotic cascade through Fas receptor in this cell line, as glycine-conjugated bile acids do in hepatocytes [ 25 ] . However, the activation of caspases does not require a specific kind of bile acid transporter since TCA is not toxic to McArdle RH-7777 cells irrespective of whether these cells internalize bile acids via ntcp or asbt.
At present, it is not known how conjugated bile acids activate caspases in CHO.asbt.