Example sentences for: caspases

How can you use “caspases” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • 4), indicating that cleavage of Golgi autoantigens during apoptosis is mediated by caspases.

  • Bcl-2 impedes the subcellular trafficking of p53, inhibits downstream adapters necessary for stimulation of the apoptotic caspases, and can act as an antioxidant [ 15 28 ] .

  • The cleavage of calpastatin by caspases initiates the apoptotic cascade in certain neurological disorders [ 20 ] . It is possible that increased expression of calpastatin may control calpain activity thereby limiting extent of proteolysis during capillary sprouting.

  • Lane et al . reported recently that the Golgi complex in HeLa cells is fragmented into scattered vesicles by caspases due to interference of Golgi reassembly and abnormalities of the 65 kDa stacking protein GRASP65 [ 32 ] . In the present report, we describe characteristic changes of the Golgi complex during the progression of apoptosis.

  • The loss of cytochrome c causes a break in the electron transfer chain resulting in the production of reactive oxygen species [ 31 ] . Reactive oxygen species are known to cause the oxidation and loss of function of many lipids including cardiolipin [ 20 ] . Finally, caspases activated downstream of cytochrome c release have been implicated in mitochondrial damage [ 29 ] . It appears likely that the cumulative damage of these agents could lead to the irreversible loss of mitochondrial membrane integrity and structure.


How many words do you know? Try our free vocabulary size test!


Search

Search for example sentences

Loading Loading...
Quantcast