Example sentences for: caspase-

How can you use “caspase-” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • For quantification of cells expressing Nestin, Ki67, β-tubulin III, activated caspase-3, insulin, or C-peptide, NS-derived cell clusters were fixed, and sectioned to generate 7-μm-thick tissue sections.

  • Earlier studies have shown that blockade of caspase-8 activation in HeLa cells and deletion of caspase-8 in Jurkat cells prevented activation of downstream signaling, resulting in a failure of the cells to undergo apoptosis in response to TRAIL [ 46 ] . Similarly, another group has demonstrated that apoptosis induced by S. aureus in bovine mammary epithelial (MAC-T) cells utilizes a mechanism involving caspases-8 and -3, which are two key components of the proteolytic cascade that leads to apoptosis [ 30 ] . Results from the current study demonstrate a two-fold increase in caspase-8 activation upon infection with S. aureus (Fig.

  • Activated caspase-8 was detected in uninfected control osteoblast cultures (Fig.

  • [ 30 ] demonstrated host caspases-8 and -3 to play a role in S. aureus -induced apoptosis, and caspase-8 is known to be associated with apoptosis triggered by engagement of death receptors [ 35 ] . Several recent studies have associated microbial induction of apoptosis with the production of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL).

  • As a positive control, osteoblasts were stimulated with cycloheximide (CHX), a compound known to induce caspase-8 activation [ 45 ] . At various times post-infection, endogenous caspase-8 activity was quantified.


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