Example sentences for: caspase-

How can you use “caspase-” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Expression of apoptosis-related molecules, such as Bcl-xS, Bax, and caspase-3, seems to be little regulated in the early stage of this vessel remodeling process.

  • A recent report demonstrated that S. aureus -induced apoptosis of epithelial cells involves activation of caspases-8 and-3 [ 30 ] . To determine whether caspase-8 is activated in S. aureus -infected osteoblasts, cultured normal mouse osteoblasts were infected with S. aureus strain UAMS-1 at various MOIs.

  • Cytosolic extracts (300 μg protein) were assayed for caspase-3 activity according to the protocol described in the EnzChek Caspase-3 Assay Kit (Molecular Probes).

  • The signaling pathways of TRAIL and its receptors are not fully known [ 50 ] ; however, recent studies suggest TRAIL activates pathways similar to those activated by TNF and its receptors [ 49 ] . Binding of TRAIL to death-domain containing receptors can cause apoptosis via activation of caspase-8 in Jurkat and HeLa cells [ 46 49 ] .

  • These data, along with the previous studies that confirmed morphological evidence of apoptosis and biochemical evidence of caspase-3 activation in these kidneys [ 7 ] , showed a role for the Fas/FasL pathway in promoting the loss of kidney function that develops in the setting of hypertensive nephrosclerosis in this model.


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