Example sentences for: caspase-activated

How can you use “caspase-activated” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Perhaps the most prominent caspase 3 substrate is DNA Fragmentation Factor 45 (DFF45), an inhibitor of caspase-activated DNase [ 26 ] . Following caspase 3-mediated cleavage, DFF45 releases DFF40, the DNase responsible for DNA fragmentation into the characteristic apoptotic DNA ladder.

  • Cytochrome c is then released from the mitochondria into the cytosol, where it interacts with downstream proapoptotic proteins such as Apaf-1 and caspase 9. Activation of these proteins further activates nucleases, such as caspase-activated DNase (CAD), which cause DNA fragmentation.


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