Example sentences for: caspase

How can you use “caspase” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • To determine whether elevated levels of cleaved caspase 3 resulted in increased cleavage of caspase 3 substrates, DFF45 cleavage was studied (Figure 3).

  • No difference was detected in the levels of caspase 9 or caspase 8 among the BRCA1+ or BRCA1wt cells, suggesting that the reduced cell survival in BRCA1+ cells was not associated with a difference in initiation of either the mitochondrial or the Fas/FasL apoptotic pathways.

  • To determine which key pathways were activated, Western blot analyses of phosphorylated or cleaved proteins in E15+2 CONT and SN50-treated explants were conducted as previously described [ 5 ] . For this set of experiments, we first determined the specificity for each of the following antibodies purchased from Cell Signaling Technology (Beverly, MA) using E15 and E17 SMG homogenates: anti-phosphorylated Erk1/2 [phospho-p44/42 MAP kinase (Thr202/Tyr204)] antibody, anti-phosphorylated c-Raf(Ser259) antibody, anti-cleaved Caspase 3 (D 175) antibody, and anti-cleaved PARP (D214) antibody.

  • However, the different profile of caspase 8 activation suggests that taurine- and glycine-conjugated bile acids may trigger apoptosis by different pathways.

  • 24 cells [ 1 ] concordant with what has been documented in hepatocytes [ 19 ] . Consistent with the induction of apoptotic cell death; GCDCA, but not TCA, preferentially induced the activation of the initiator caspase 8 in McNtcp.


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