Example sentences for: caspase

How can you use “caspase” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • This mutation, common among families with hereditary ovarian cancer, is a frameshift mutation occurring at the beginning of the C 3 HC 4 region of exon 2 that essentially interrupts RING domain function [ 19 29 30 ] . The results showed that disruption of the BRCA1 amino-terminal RING domain altered caspase 3 activation and subsequent DFF45 and PARP cleavage, resulting in accelerated STS-induced apoptosis.

  • The effector NF-κB transcription factor of the Imd pathway is Relish, which upon immune activation is cleaved by the Dredd caspase (Figure 2).

  • Fas associated death domain, FADD) [ 30 ] ultimately activating members of the caspase family resulting in apoptosis.

  • Caspase activation is a key regulatory step for apoptosis [ 10 11 ] .

  • No difference was detected in the levels of caspase 9 or caspase 8 among the BRCA1+ or BRCA1wt cells, suggesting that the reduced cell survival in BRCA1+ cells was not associated with a difference in initiation of either the mitochondrial or the Fas/FasL apoptotic pathways.


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