Example sentences for: akr

How can you use “akr” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Though unlikely, the possibility of an undetected recombinational rearrangement within this region that placed an AKR/J allele of the gene that causes IPD on the AKXD28 chromosome cannot be ruled out.

  • It includes Far1p, a protein necessary for pheromone-induced cell cycle arrest in G1 [ 11 ] , Mpt5p, a protein necessary for recovery from cell cycle arrest [ 12 ] , and Bem1p and Sph1, both of which are necessary for establishment of cell polarity during shmooing and budding [ 13 14 ] . In our protein-interaction map there is no direct interaction between a pheromone receptor (Ste2p or Ste3p) and any component of the heterotrimeric G protein complex (Ste4p/Ste18p/Gpa1p), so NetSearch drew indirect paths through Akr1p, a known inhibitor of signaling in the pheromone pathway [ 15 ] . The predicted network does not include the GTPase Cdc42p (paths were instead drawn preferentially through its cofactor Cdc24p, which physically interacts with Ste4p) or Ste20p, because of missing interactions in the protein-interaction map.

  • Several of the differentially expressed genes, including aldo-keto reductase 1C1 ( AKR1C1 ), aldehyde dehydrogenase 1A1 ( ALDH1A1 ), and alcohol dehydrogenase 1B ( ADH1B ), function in sex steroid and retinoic acid metabolism (Figure 2).

  • This genetic uniformity is important for the analysis of complex diseases because it allows repeated and therefore accurate assessment of phenotypes associated with the AKXD28 mix of D2 and AKR/J genomes.

  • An AKR/J modifier(s) likely suppresses IPD in AKXD28


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