Example sentences for: akr

How can you use “akr” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • AKXD28 mice, therefore, have a genetic background that is a mix of the D2 (glaucomatous) and AKR/J (normal eyes with no obvious disease) genomes.

  • Other explanations for the absence of an IPD phenotype in AKXD28 include: inheritance of an AKR/J modifier gene(s) that suppresses the IPD phenotype, a spontaneous reversion of the ipd mutation in AKXD28 mice, or the spontaneous occurrence and fixation of the ipd mutation in strain D2 after the derivation of the AKXD28 strain.

  • Known characteristics of the AKR/J and D2 strains offer few clues to AKXD28's increased susceptibility to pressure-induced damage and all explanatory attempts are speculative.

  • Though unlikely, the possibility of an undetected recombinational rearrangement within this region that placed an AKR/J allele of the gene that causes IPD on the AKXD28 chromosome cannot be ruled out.

  • Inheritance of an AKR/J modifier seems the most likely explanation but elucidation of the molecular nature of the ipd mutation or the mapping of a modifier gene(s) is necessary to distinguish among the possibilities.


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